INFLUENCE OF SOMATIC MUTATIONS OF KRAS, NRAS, BRAF AND MICROSATELLITE INSTABILITY STATUS ON SURVIVAL OF COLORECTAL CANCER PATIENTS WITH PERITONAL CARCINO

INFLUENCE OF SOMATIC MUTATIONS OF KRAS, NRAS, BRAF AND MICROSATELLITE INSTABILITY STATUS ON SURVIVAL OF COLORECTAL CANCER PATIENTS WITH PERITONAL CARCINO

Purpose: to evaluate the effect of somatic mutations of the KRAS, NRAS, BRAF genes and the status of microsatellite instability on the overall and disease-free survival of patients undergoing cytoreductive surgery with hyperthermic intraperitoneal chemotherapy.Material and Methods. From 2012 to 2018...

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Bibliographic Details
Main Authors: V. P. Shubin, Yu. A. Shelygin, S. I. Achkasov, O. I. Sushkov, A. A. Ponomarenko, A. I. Arzamastseva, A. S. Tsukanov
Format: Article
Language:Russian
Published: Russian Academy of Sciences, Tomsk National Research Medical Center 2020-10-01
Series:Сибирский онкологический журнал
Subjects:
colorectal cancer
peritoneal carcinomatosis
kras
nras
braf
msi status
survival
Online Access:https://www.siboncoj.ru/jour/article/view/1579
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