Immunogenicity of various variants of Ebola and Marburg virus glycoprotein genes in recombinant adenoviral vectors

Immunogenicity of various variants of Ebola and Marburg virus glycoprotein genes in recombinant adenoviral vectors

INTRODUCTION. Marburg and Ebola viruses cause severe haemorrhagic fever in humans and primates. Currently, there are no licensed prophylactic vaccines that can simultaneously prevent the spread or reduce the severity of both diseases caused by these filoviruses. The development of effective prophyla...

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Main Authors: T. A. Ozharovskaia, O. V. Zubkova, O. Popova, A. V. Kovyrshina, P. P. Goldovskaya, I. V. Vavilova, I. V. Dolzhikova, E. I. Ermolova, M. S. Kunda, N. N. Ryzhova, O. L. Voronina, D. N. Shcherbinin, D. V. Shcheblyakov, D. Y. Logunov, A. L. Gintsburg
Format: Article
Language:Russian
Published: Ministry of Health of the Russian Federation. Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» 2024-10-01
Series:Биопрепараты: Профилактика, диагностика, лечение
Subjects:
immunogenicity
glycoprotein gene variants
ebola virus
marburg virus
human adenovirus type 5
recombinant adenoviral vectors
ebola virus disease
marburg virus disease
humoral immune response
Online Access:https://www.biopreparations.ru/jour/article/view/576
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