Ultrasound and Microwave-Assisted Synthesis and Antidiabetic and Hematopoietic Activity of Diphenhydramine Derivatives

QR Code

Ultrasound and Microwave-Assisted Synthesis and Antidiabetic and Hematopoietic Activity of Diphenhydramine Derivatives

This study presents the synthesis and antidiabetic and hematopoietic activity of ionic compounds based on 2-(diphenylmethoxy)-<i>N</i>,<i>N</i>-dimethylethanamine (diphenhydramine). Synthesis is carried out under ultrasonic (US) and microwave (MW) irradiation as well as using...

Full description

Saved in:

Bibliographic Details
Main Authors:	Anuar Dauletbakov, Yelizaveta Belyankova, Saniya Assylbekova, Darya Zolotareva, Sarah Bayazit, Layilya Baktybayeva, Ulan Kemelbekov, Valentina Yu, Nailya Ibragimova, Alexey Zazybin
Format:	Article
Language:	English
Published:	MDPI AG 2025-07-01
Series:	Molecules
Subjects:	antidiabetic activity α-glucosidase inhibition α-amylase inhibition hematopoietic activity microwave synthesis ultrasonic synthesis
Online Access:	https://www.mdpi.com/1420-3049/30/14/2967
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Exploring the inhibitory effect and mechanism of 3,4,5-trihydroxybiphenyl on α-glucosidase: an integrated experimental and computational approach
by: Ruofan Guo, et al.
Published: (2025-07-01)

Simultaneous ultrasonication on the extraction, antioxidant capacity, and α-glucosidase inhibition activity of polysaccharide from burdock (Arctium lappa L.)
by: Shakti Chandra Mondal, et al.
Published: (2025-12-01)

Antihyperglycemic Activity of <i>Alchemilla viridiflora</i> Herb Methanol Extract in Streptozotocin-Induced Diabetic Male Rats
by: Jelena S. Radović Selgrad, et al.
Published: (2025-06-01)

One-Pot Synthesis of Novel Pyrimidine Derivatives with Potential Antidiabetic Activity Through Dual α-Glucosidase and α-Amylase Inhibitors
by: Ohood Al-Shehri, et al.
Published: (2025-07-01)

In Vitro Antioxidant Potential, Antidiabetic Activities, and GC–MS Analysis of Lipid Extracts of <i>Chlorella</i> Microalgae
by: Somruthai Kaeoboon, et al.
Published: (2025-06-01)

α-Glucosidase inhibitory activity of polyphenol-rich sugarcane extract: screening and mechanistic insights based on biolayer interferometry-mass spectrometry
by: Mengli Yao, et al.
Published: (2025-07-01)

Antioxidant, Antidiabetic and Anticancer Effects of Persimmon Leave Extracts In vitro
by: Doaa, F. Hassan, et al.
Published: (2023-09-01)

Functional Properties of <i>Campomanesia xanthocarpa</i> Infusions: Phenolic Profile, Digestive Stability, Enzyme Inhibition, and Glycemic Effects
by: Cristiane Maria Chitolina Tremea, et al.
Published: (2025-07-01)

Heterostilbene Carbamates with Selective and Remarkable Butyrylcholinesterase Inhibition: Computational Study and Physico-Chemical Properties
by: Anamarija Raspudić, et al.
Published: (2025-06-01)

In Vitro Effects of Some Antibiotics on Purified β-Glucosidases from Rat Liver and Kidney Tissues
by: Hatibe Kara, et al.
Published: (2025-05-01)

In silico and in vitro studies of flavanoid content of Uncaria gambir Roxb stem extract on antidiabetic activity
by: Ainun Fawaid, et al.
Published: (2025-07-01)

Exploring Biomedical Potential of Phytochemical Synthesized Iron Nanoparticles: In Vivo and In Vitro Evaluation
by: Sumaira Mumtaz, et al.
Published: (2025-06-01)

Molecular Docking and Pharmacoinformatics Study of Bioactive Compounds in Sweet Flag (Acorus calamus L.) as Antidiabetic Agents Targeting α-Glucosidase
by: Rani Sakila Nasution, et al.
Published: (2025-06-01)

ANTIDIABETIC ACTIVITY OF GUANIDINIUM SALT 2-AMINOPHENYLACETATE
by: E. V. Ponomarenko
Published: (2019-01-01)

Biogenic synthesis of silver nanoparticles using methanolic extracts of Ulva lactuca: GC/MS analysis, antibacterial, antioxidant, and antidiabetic activity
by: N.V. Mrunalini, et al.
Published: (2025-10-01)

Inhibitory effect of extract from Capsicum annuum leaves against α-glucosidase activity
by: LI Chunying, et al.
Published: (2013-03-01)

Evaluation of Antioxidants, Antibacterial and Antidiabetic Activities of Aqua-alcoholic Marjoram Extract
by: Kadhim K. Ghudhaib, et al.
Published: (2024-08-01)

Selection and in vitro Probiotic Properties of Bifidobacterium longum subsp. longum with Anti-diabetic Activity from the Intestinal Tract of Chinese Tajik Children
by: LI Si, AN Meiling, LI Longlong, ZHANG Ruirui, SUN Hailong, NI Yongqing
Published: (2025-05-01)

Synthesis of aryl hydrazone derivatives for α-naphthalide and benzothiazolide
by: Luma S. Ahamed, et al.
Published: (2024-10-01)

Identification of α-Amylase Inhibitory Peptides from Tryptic Hydrolysate of <i>Caulerpa racemosa</i> Green Algae Protein
by: Izatul Husna, et al.
Published: (2025-07-01)

Thymus praecox subsp. polytrichus: Antimicrobial and antidiabetic activity of ethanol extracts
by: Grujić Slavica M., et al.
Published: (2025-01-01)

Effect of in Vitro Simulated Digestion on Changes in Chemical Composition, Functional Activity and Saponins of Panax notoginseng Leaves
by: HAN Mingchong, LI Yunqian, WANG Yihui, ZHANG Xuechun, FANG Yue, XIANG Ping, HUA Yan, LI Tianli, HE Xiahong, WANG Zhenxing
Published: (2025-06-01)

Extraction of Polysaccharides from Black Corncob Using Ultrasonic-assisted Deep Eutectic Solvent and Its Activity in Inhibiting α-Glycosidase
by: Han YUN, et al.
Published: (2025-07-01)

Evaluating the in vitro anti-diabetic activity of Bryonia dioica root extracts supported by molecular docking analysis
by: Fekhikher Zohra, et al.
Published: (2025-06-01)

Hypericum empetrifolium subsp. empetrifolium: an assessment of its antifungal, antidiabetic, anti-aging, and neuroprotective potential
by: Serpil Demirci Kayıran, et al.
Published: (2025-07-01)

Structural characterization and preliminary functional evaluation of a novel Polysaccharide NS0-1 from Nostoc sphaeroides Kütz
by: Wang Rui, et al.
Published: (2025-01-01)

GC-MS analysis, comprehensive biological profiling, molecular docking and ADMET studies of Ficus vasta Forssk. n-hexane extract
by: Hanan Y. Aati, et al.
Published: (2025-12-01)

Antioxidant and alpha-glucosidase inhibitory activities of flavonoids isolated from fermented leaves of Camellia chrysantha (Hu) Tuyama
by: Tran Thi Nhu Hang, et al.
Published: (2025-05-01)

Screening and identification of lactic acid bacteria with α-glucosidase inhibiting activity
by: Yi Liu, et al.
Published: (2025-07-01)

Glycosidase Isoforms in Honey and the Honey Bee (<i>Apis mellifera</i> L.): Differentiating Bee- and Yeast-Derived Enzymes and Implications for Honey Authentication
by: Ratko Pavlović, et al.
Published: (2025-06-01)

Prevalence of Tonsillitis caused by Streptococcus spp. Among children and the effect of some Lactic acid bacterial (LAB) strain on it
by: Baghdad Science Journal
Published: (2016-06-01)

Study of synergistic Inhibitory effectiveness of mixed of Sweet bell pepper extract and virgin olive oil in α -amylase and α-glucosidase activity in serum of male rats infected with experimental diabetes
by: Wedad M. Lahmood Al-obaidi
Published: (2023-02-01)

Effects of <i>Periploca chevalieri</i> Browicz on Postprandial Glycemia and Carbohydrate-Hydrolyzing Enzymes
by: Katelene Lima, et al.
Published: (2025-06-01)

α-Glucosidase, Angiotensin-converting Enzyme, and Acetylcholinesterase Inhibitory Activities of a Marine Red Alga Galaxaura oblongata
by: Kimnard Joseph Magsacay Duat, et al.
Published: (2023-09-01)

Synthesis, Characterization, and <i>In-Silico</i> Studies of Some Novel Phenylhydrazone Derivatives as Potential Agents for Antimicrobial Activities
by: Rabiu Bako, et al.
Published: (2024-11-01)

Flavonoids as Antidiabetic Agents, Challenges and Future Directions
by: Qamar Uddin Ahmed
Published: (2025-07-01)

Effect of Sugarcane Polyphenol Extract on α-Amylase Inhibition and Mechanism Exploration
by: Yumei Wang, et al.
Published: (2025-06-01)

Cannabinoid Modulation of Excitability and Short-Term Neuronal Dynamics in the Dorsal and Ventral Hippocampus
by: Giota Tsotsokou, et al.
Published: (2025-05-01)

Study on an α-glucosidase inhibitor separated from Cyclocarya paliurus leaves
by: Shen Bing, et al.
Published: (2014-05-01)

Prospects for the Search for New Antidiabetic Agents Among Vanadium-containing Complex Compounds (Review)
by: A. I. Krasnova, et al.
Published: (2023-12-01)