Case report of a squamous cell carcinoma arising in a vulvar cutaneous horn

Background: Cutaneous horns are rare lesions that consist of a proliferation of keratotic material, often representing animal horns. Rarely, they may be associated with underlying squamous cell carcinomas. Here, we present a case report of a cutaneous horn arising in a squamous cell carcinoma of the...

Full description

Saved in:
Bibliographic Details
Main Authors: Michael Bell, Erin Crane, Robert Tucker Burks
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Gynecologic Oncology Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352578925001092
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background: Cutaneous horns are rare lesions that consist of a proliferation of keratotic material, often representing animal horns. Rarely, they may be associated with underlying squamous cell carcinomas. Here, we present a case report of a cutaneous horn arising in a squamous cell carcinoma of the vulva. Objective: In this report, we highlight the case of an 84 year-old patient who presented with a vulvar cutaneous horn. After resection, pathology demonstrated an invasive squamous cell carcinoma of the vulva. We provide a review of available literature and describe a rare manifestation of a squamous cell carcinoma of the vulva. Given her frailty, no further treatment was pursued, and she remains in observation without evidence of recurrence. Conclusions: Our case highlights a rare presentation of a vulvar cutaneous horn arising within invasive squamous cell carcinoma of the vulva. While most cutaneous horns are benign, a subset may harbor malignancy, and therefore excision is warranted. Additional treatment is dependent upon histopathology, disease site, and patient factors.
ISSN:2352-5789