RNA synthesis in Leishmania donovani is constitutive during stage conversion: a genome-wide PRO-seq analysis
ABSTRACT Transcription in Leishmania donovani has long been considered constitutive, as shown by nuclear run-on analyses and northern blots, with gene expression primarily regulated post-transcriptionally. Using precision nuclear run-on sequencing (PRO-seq), we investigated active transcription in a...
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Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2025-07-01
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Series: | Microbiology Spectrum |
Subjects: | |
Online Access: | https://journals.asm.org/doi/10.1128/spectrum.00566-25 |
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