Partially hydrolyzed, whey-based infant formula with six human milk oligosaccharides, B. infantis LMG11588, and B. lactis CNCM I-3446 is safe, well tolerated, and improves gut health: a staged analysis of a randomized trial

Background and aimsGut health and microbiome development are closely linked in early life, with human milk oligosaccharides (HMOs) playing a key role. This study reports results through 4 months of age from a trial evaluating an infant formula containing a synbiotic blend of HMOs and probiotics, foc...

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Main Authors:	Jean-Charles Picaud, Olivier Claris, Mercedes Gil-Campos, Ignacio Salamanca De La Cueva, Luc Cornette, Philippe Alliet, André Léké, Mireille Castanet, Hugues Piloquet, Virginie de Halleux, Delphine Mitanchez, Yvan Vandenplas, Pierre Maton, Frank Jochum, Dirk Olbertz, Sergio Negre Policarpo, Luca Lavalle, Cecilia Fumero, Paula Rodriguez-Garcia, Janne Marie Moll, Irma Silva-Zolezzi, Boutaina Zemrani, Nicholas P. Hays, Norbert Sprenger, Javier Miranda-Mallea
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-07-01
Series:	Frontiers in Nutrition
Subjects:	bifidobacteria gastrointestinal tolerance growth gut health microbiota
Online Access:	https://www.frontiersin.org/articles/10.3389/fnut.2025.1628847/full
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Partially hydrolyzed, whey-based infant formula with six human milk oligosaccharides, B. infantis LMG11588, and B. lactis CNCM I-3446 is safe, well tolerated, and improves gut health: a staged analysis of a randomized trial

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