The Effect of Cytochrome P450 and Organic Anion Transporter Polypeptide on Macrolides–Atorvastatin Drug Interaction

Cytochrome P450 (CYP3A4) enzymes and organic anion-transporting polypeptides (OATPs) are critical in drug pharmacokinetics. Fifteen rabbits were divided into three groups: the atorvastatin group received a single oral dose of atorvastatin (0.86 mg/kg B.W.); the clarithromycin-atorvastatin group rec...

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Autori principali: Zainab Farooq Abdalhameed, Orooba Mohammed Saeed Ibrahim
Natura: Articolo
Lingua:inglese
Pubblicazione: Corporation of Research and Industrial Development 2025-06-01
Serie:Iraqi Journal of Industrial Research
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Accesso online:https://ijoir.gov.iq/ijoir/index.php/jou/article/view/498
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