Local Iontophoretic Application for Pharmacological Induction of Long-Term Synaptic Depression

Local Iontophoretic Application for Pharmacological Induction of Long-Term Synaptic Depression

Long-term depression (LTD), a key form of synaptic plasticity, is typically induced through regulated Ca2+ entry via NMDA receptors and achieved by prolonged (up to hundreds of seconds) low-frequency presynaptic stimulation or bath application of NMDA receptor agonists. Electrophysiological approach...

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Main Authors: Borys Olifirov, Oleksandra Fedchenko, Alexandr Dovgan, Daria Babets, Volodymyr Krotov, Volodymyr Cherkas, Pavel Belan
Format: Article
Language:English
Published: Bio-protocol LLC 2025-06-01
Series:Bio-Protocol
Online Access:https://bio-protocol.org/en/bpdetail?id=5338&type=0
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