Muscular Weakness and Loss of Motor Skills in Patients with Cerebral Palsy
Various aspects of muscle strength decrease and loss of motor skills in patients with cerebral palsy (CP) are considered in this review. Pathophysiological mechanisms caused by primary damage and reorganization of central nervous system (CNS), structural-functional changes of muscle tissue, biomecha...
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| Format: | Article |
| Language: | English |
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"Paediatrician" Publishers LLC
2020-06-01
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| Series: | Вопросы современной педиатрии |
| Subjects: | |
| Online Access: | https://vsp.spr-journal.ru/jour/article/view/2376 |
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| author | Olga A. Klochkova Alexey L. Kurenkov |
| author_facet | Olga A. Klochkova Alexey L. Kurenkov |
| author_sort | Olga A. Klochkova |
| collection | DOAJ |
| description | Various aspects of muscle strength decrease and loss of motor skills in patients with cerebral palsy (CP) are considered in this review. Pathophysiological mechanisms caused by primary damage and reorganization of central nervous system (CNS), structural-functional changes of muscle tissue, biomechanical disbalance are described. Changes at patients with CP equate with sarcopenia (physiological process of muscle strength and function loss in elderly patients). It has been shown that patients with cerebral palsy have such phenomenon as «early aging» of musculo-skeletal system. Potential approaches for prevention of sarcopenia in children and adults with cerebral palsy are discussed. Understanding of the described mechanisms of primary and age-related changes in muscle tissue in early CNS injuries is necessary to plan the activities of daily living for patients, choose the correct rehabilitation tactics, minimize adverse therapeutic effects, and reasonable management of comorbid conditions. |
| format | Article |
| id | doaj-art-3ffbf8a7aaab4e3a95a6f35a19b820d7 |
| institution | Matheson Library |
| issn | 1682-5527 1682-5535 |
| language | English |
| publishDate | 2020-06-01 |
| publisher | "Paediatrician" Publishers LLC |
| record_format | Article |
| series | Вопросы современной педиатрии |
| spelling | doaj-art-3ffbf8a7aaab4e3a95a6f35a19b820d72025-08-04T13:09:40Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352020-06-0119210711510.15690/vsp.v19i2.21031870Muscular Weakness and Loss of Motor Skills in Patients with Cerebral PalsyOlga A. Klochkova0Alexey L. Kurenkov1National Medical Research Center for Children's HealthNational Medical Research Center for Children's HealthVarious aspects of muscle strength decrease and loss of motor skills in patients with cerebral palsy (CP) are considered in this review. Pathophysiological mechanisms caused by primary damage and reorganization of central nervous system (CNS), structural-functional changes of muscle tissue, biomechanical disbalance are described. Changes at patients with CP equate with sarcopenia (physiological process of muscle strength and function loss in elderly patients). It has been shown that patients with cerebral palsy have such phenomenon as «early aging» of musculo-skeletal system. Potential approaches for prevention of sarcopenia in children and adults with cerebral palsy are discussed. Understanding of the described mechanisms of primary and age-related changes in muscle tissue in early CNS injuries is necessary to plan the activities of daily living for patients, choose the correct rehabilitation tactics, minimize adverse therapeutic effects, and reasonable management of comorbid conditions.https://vsp.spr-journal.ru/jour/article/view/2376cerebral palsysarcopeniaspasticityanabolic resistancemuscle strength |
| spellingShingle | Olga A. Klochkova Alexey L. Kurenkov Muscular Weakness and Loss of Motor Skills in Patients with Cerebral Palsy Вопросы современной педиатрии cerebral palsy sarcopenia spasticity anabolic resistance muscle strength |
| title | Muscular Weakness and Loss of Motor Skills in Patients with Cerebral Palsy |
| title_full | Muscular Weakness and Loss of Motor Skills in Patients with Cerebral Palsy |
| title_fullStr | Muscular Weakness and Loss of Motor Skills in Patients with Cerebral Palsy |
| title_full_unstemmed | Muscular Weakness and Loss of Motor Skills in Patients with Cerebral Palsy |
| title_short | Muscular Weakness and Loss of Motor Skills in Patients with Cerebral Palsy |
| title_sort | muscular weakness and loss of motor skills in patients with cerebral palsy |
| topic | cerebral palsy sarcopenia spasticity anabolic resistance muscle strength |
| url | https://vsp.spr-journal.ru/jour/article/view/2376 |
| work_keys_str_mv | AT olgaaklochkova muscularweaknessandlossofmotorskillsinpatientswithcerebralpalsy AT alexeylkurenkov muscularweaknessandlossofmotorskillsinpatientswithcerebralpalsy |