Clinical features of coronavirus infection COVID-19 in patients with arterial hypertension

The COVID-19 coronavirus pandemic is significant for modern medical science and practice. Patients with concomitant pathology during the COVID-19 pandemic, in particular arterial hypertension, require special attention, as they are among the most vulnerable groups to this infection. This requires op...

Full description

Saved in:
Bibliographic Details
Main Authors: I. A. Demina, A. G. Komarova, M. V. Ilyina, A. A. Ploskireva
Format: Article
Language:Russian
Published: Open Systems Publication 2022-04-01
Series:Лечащий Врач
Subjects:
Online Access:https://journal.lvrach.ru/jour/article/view/915
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1839591378956320768
author I. A. Demina
A. G. Komarova
M. V. Ilyina
A. A. Ploskireva
author_facet I. A. Demina
A. G. Komarova
M. V. Ilyina
A. A. Ploskireva
author_sort I. A. Demina
collection DOAJ
description The COVID-19 coronavirus pandemic is significant for modern medical science and practice. Patients with concomitant pathology during the COVID-19 pandemic, in particular arterial hypertension, require special attention, as they are among the most vulnerable groups to this infection. This requires optimization of diagnostic and clinical approaches to helping patients with this pathology. In this regard, the study of the course of the infectious process COVID-19 in patients with hypertension is of scientific and practical interest. On the basis of the State Budgetary Healthcare Institution S. P. Botkin City Clinical Hospital of the Moscow Department of Health 145 patients with COVID-19 were under observation, 91 of whom had a coronavirus infection combined with arterial hypertension, 54 patients had no arterial hypertension. All patients underwent a comprehensive clinical and laboratory examination and clinical follow-up in dynamics. The course of COVID-19 coronavirus infection in patients with arterial hypertension is characterized by the development of more severe pneumonia (in 5,5% of patients with hypertension, lung lesions are diagnosed with computed tomography of more than 3 degrees) and more pronounced respiratory failure in a larger number of patients (in 8,8% with hypertension, infection was accompanied by the development of respiratory failure of 2 or more degrees). Patients with hypertension had higher rates of CRP, ferritin and glucose, while changes in the leukocyte formula were comparable between the groups. The dynamics of the level of postinfectious IgG class antibodies was characterized by a gradual decrease in their level during the year, while in patients with COVID-19 occurring against the background of hypertension, higher rates of postinfectious IgG class antibodies were observed on average in the first months after infection. The development of coronavirus infection COVID-19 in patients with particular arterial hypertension requires special attention from the doctor, due to the risk of developing a severe form of infection.
format Article
id doaj-art-3fe1cf5ee0b541c79c17a9ff6a19fb18
institution Matheson Library
issn 1560-5175
2687-1181
language Russian
publishDate 2022-04-01
publisher Open Systems Publication
record_format Article
series Лечащий Врач
spelling doaj-art-3fe1cf5ee0b541c79c17a9ff6a19fb182025-08-03T13:02:54ZrusOpen Systems PublicationЛечащий Врач1560-51752687-11812022-04-0104545910.51793/OS.2022.25.4.010910Clinical features of coronavirus infection COVID-19 in patients with arterial hypertensionI. A. Demina0A. G. Komarova1M. V. Ilyina2A. A. Ploskireva3State Budgetary Healthcare Institution S. P. Botkin City Clinical Hospital of the Moscow Department of HealthState Budgetary Healthcare Institution S. P. Botkin City Clinical Hospital of the Moscow Department of HealthState Budgetary Healthcare Institution S. P. Botkin City Clinical Hospital of the Moscow Department of HealthFederal State Autonomous Educational Institution of Higher Education Pirogov Russian National Research Medical University Ministry of Health of the Russian Federation; Federal Budgetary Institution of Science Central Research Institute of Epidemiology of RospotrebnadzorThe COVID-19 coronavirus pandemic is significant for modern medical science and practice. Patients with concomitant pathology during the COVID-19 pandemic, in particular arterial hypertension, require special attention, as they are among the most vulnerable groups to this infection. This requires optimization of diagnostic and clinical approaches to helping patients with this pathology. In this regard, the study of the course of the infectious process COVID-19 in patients with hypertension is of scientific and practical interest. On the basis of the State Budgetary Healthcare Institution S. P. Botkin City Clinical Hospital of the Moscow Department of Health 145 patients with COVID-19 were under observation, 91 of whom had a coronavirus infection combined with arterial hypertension, 54 patients had no arterial hypertension. All patients underwent a comprehensive clinical and laboratory examination and clinical follow-up in dynamics. The course of COVID-19 coronavirus infection in patients with arterial hypertension is characterized by the development of more severe pneumonia (in 5,5% of patients with hypertension, lung lesions are diagnosed with computed tomography of more than 3 degrees) and more pronounced respiratory failure in a larger number of patients (in 8,8% with hypertension, infection was accompanied by the development of respiratory failure of 2 or more degrees). Patients with hypertension had higher rates of CRP, ferritin and glucose, while changes in the leukocyte formula were comparable between the groups. The dynamics of the level of postinfectious IgG class antibodies was characterized by a gradual decrease in their level during the year, while in patients with COVID-19 occurring against the background of hypertension, higher rates of postinfectious IgG class antibodies were observed on average in the first months after infection. The development of coronavirus infection COVID-19 in patients with particular arterial hypertension requires special attention from the doctor, due to the risk of developing a severe form of infection.https://journal.lvrach.ru/jour/article/view/915sars-cov-2coronavirus infectioncovid-19arterial hypertensionrenin-angiotensin-aldosterone systemclinical features of covid-19
spellingShingle I. A. Demina
A. G. Komarova
M. V. Ilyina
A. A. Ploskireva
Clinical features of coronavirus infection COVID-19 in patients with arterial hypertension
Лечащий Врач
sars-cov-2
coronavirus infection
covid-19
arterial hypertension
renin-angiotensin-aldosterone system
clinical features of covid-19
title Clinical features of coronavirus infection COVID-19 in patients with arterial hypertension
title_full Clinical features of coronavirus infection COVID-19 in patients with arterial hypertension
title_fullStr Clinical features of coronavirus infection COVID-19 in patients with arterial hypertension
title_full_unstemmed Clinical features of coronavirus infection COVID-19 in patients with arterial hypertension
title_short Clinical features of coronavirus infection COVID-19 in patients with arterial hypertension
title_sort clinical features of coronavirus infection covid 19 in patients with arterial hypertension
topic sars-cov-2
coronavirus infection
covid-19
arterial hypertension
renin-angiotensin-aldosterone system
clinical features of covid-19
url https://journal.lvrach.ru/jour/article/view/915
work_keys_str_mv AT iademina clinicalfeaturesofcoronavirusinfectioncovid19inpatientswitharterialhypertension
AT agkomarova clinicalfeaturesofcoronavirusinfectioncovid19inpatientswitharterialhypertension
AT mvilyina clinicalfeaturesofcoronavirusinfectioncovid19inpatientswitharterialhypertension
AT aaploskireva clinicalfeaturesofcoronavirusinfectioncovid19inpatientswitharterialhypertension