The first experience of orthotropic implantation of decellularized mitral allograft
Traditional biological and mechanical valve substitutes have some well-known limitation, such as rapid deterioration of the tissue ones in young patient and the high risk of thrombosis and anticoagulation therapy complications for the mechanical ones. At the same time the aortic and pulmonary valves...
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Academician I.P. Pavlov First St. Petersburg State Medical University
2015-09-01
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| Series: | Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова |
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| Online Access: | https://www.sci-notes.ru/jour/article/view/139 |
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| _version_ | 1839574695826948096 |
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| author | P. P. Yablonsky S. M. Yashin |
| author_facet | P. P. Yablonsky S. M. Yashin |
| author_sort | P. P. Yablonsky |
| collection | DOAJ |
| description | Traditional biological and mechanical valve substitutes have some well-known limitation, such as rapid deterioration of the tissue ones in young patient and the high risk of thrombosis and anticoagulation therapy complications for the mechanical ones. At the same time the aortic and pulmonary valves can already be replaced with decellularized allografts that showed promising results in terms of both hemodynamics and reliability while anticoagulation for them is not needed. This paper describes the first orthotropic implantation of the decellularized mitral valve allograft in sheep model. The original method without stabilizing ring is described, which have shown good echocardiographic results. |
| format | Article |
| id | doaj-art-3f3f6d89d0894c24b904ebcd511b5bbf |
| institution | Matheson Library |
| issn | 1607-4181 2541-8807 |
| language | Russian |
| publishDate | 2015-09-01 |
| publisher | Academician I.P. Pavlov First St. Petersburg State Medical University |
| record_format | Article |
| series | Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова |
| spelling | doaj-art-3f3f6d89d0894c24b904ebcd511b5bbf2025-08-04T13:14:00ZrusAcademician I.P. Pavlov First St. Petersburg State Medical UniversityУчёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова1607-41812541-88072015-09-01223646510.24884/1607-4181-2015-22-3-64-65135The first experience of orthotropic implantation of decellularized mitral allograftP. P. Yablonsky0S. M. Yashin1Первый Санкт-Петербургский государственный медицинский университет имени академика И.П. Павлова; Исследовательская лаборатория биотехнологий и искусственных органов имени Г. В. Лейбница Медицинского университета ГанновераПервый Санкт-Петербургский государственный медицинский университет имени академика И.П. Павлова; Исследовательская лаборатория биотехнологий и искусственных органов имени Г. В. Лейбница Медицинского университета ГанновераTraditional biological and mechanical valve substitutes have some well-known limitation, such as rapid deterioration of the tissue ones in young patient and the high risk of thrombosis and anticoagulation therapy complications for the mechanical ones. At the same time the aortic and pulmonary valves can already be replaced with decellularized allografts that showed promising results in terms of both hemodynamics and reliability while anticoagulation for them is not needed. This paper describes the first orthotropic implantation of the decellularized mitral valve allograft in sheep model. The original method without stabilizing ring is described, which have shown good echocardiographic results.https://www.sci-notes.ru/jour/article/view/139сердечно-сосудистая хирургияпротезирование митрального клапанадецеллюляризациямитральный аллографтcardio-vascular surgerymitral valve replacementdecellularizationmitral allograft |
| spellingShingle | P. P. Yablonsky S. M. Yashin The first experience of orthotropic implantation of decellularized mitral allograft Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова сердечно-сосудистая хирургия протезирование митрального клапана децеллюляризация митральный аллографт cardio-vascular surgery mitral valve replacement decellularization mitral allograft |
| title | The first experience of orthotropic implantation of decellularized mitral allograft |
| title_full | The first experience of orthotropic implantation of decellularized mitral allograft |
| title_fullStr | The first experience of orthotropic implantation of decellularized mitral allograft |
| title_full_unstemmed | The first experience of orthotropic implantation of decellularized mitral allograft |
| title_short | The first experience of orthotropic implantation of decellularized mitral allograft |
| title_sort | first experience of orthotropic implantation of decellularized mitral allograft |
| topic | сердечно-сосудистая хирургия протезирование митрального клапана децеллюляризация митральный аллографт cardio-vascular surgery mitral valve replacement decellularization mitral allograft |
| url | https://www.sci-notes.ru/jour/article/view/139 |
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