Regulation of hepatic Sirt1 expression and lipid metabolism through TNF receptor signaling
The production of tumor necrosis factor -alpha (TNFα) has been associated with fatty liver disease (i.e, hepatosteatosis) for many years. In fact, cytokine production has been thought of as a consequence of hepatic lipid accumulation which then becomes a critical factor in the development of chronic...
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Main Authors: | Ian N. Hines, Samuel B. Stafford, Blair U. Bradford, Michael D. Wheeler |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2025-07-01
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Series: | Frontiers in Immunology |
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Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2025.1627433/full |
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