Regulation of hepatic Sirt1 expression and lipid metabolism through TNF receptor signaling

The production of tumor necrosis factor -alpha (TNFα) has been associated with fatty liver disease (i.e, hepatosteatosis) for many years. In fact, cytokine production has been thought of as a consequence of hepatic lipid accumulation which then becomes a critical factor in the development of chronic...

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Bibliographic Details
Main Authors: Ian N. Hines, Samuel B. Stafford, Blair U. Bradford, Michael D. Wheeler
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1627433/full
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