Immunobiological Properties of <i>Francisella tularensis</i> 15/10 Strain with Deleted recA Gene

Immunobiological Properties of <i>Francisella tularensis</i> 15/10 Strain with Deleted recA Gene

Deletion of recA gene in Francisella tularensis 15/10 genome leads to the increase in its sensitivity to ultraviolet irradiation, reduction of the homologous recombination capacity, and a slight decline of virulence for mice. Efficacy of Francisella tularensis 15/10ΔrecA reproduction within micropha...

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Bibliographic Details
Main Authors: A. A. Lapin, A. N. Mokrievich, G. M. Vakhrameeva, T. I. Kombarova, I. V. Bakhteeva, I. A. Dyatlov, V. M. Pavlov
Format: Article
Language:Russian
Published: Federal Government Health Institution, Russian Research Anti-Plague Institute “Microbe” 2011-08-01
Series:Проблемы особо опасных инфекций
Subjects:
tularemia vaccine strain
<i>reca </i>gene
recombination
protective properties
Online Access:https://journal.microbe.ru/jour/article/view/707
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