Green bioanalytical method development and validation for estimation of Imeglimin hydrochloride using human plasma in pure form by LC–MS/MS

Green bioanalytical method development and validation for estimation of Imeglimin hydrochloride using human plasma in pure form by LC–MS/MS

Abstract Background A bioanalytical method was developed and validated in accordance with US FDA guidelines for estimating Imeglimin hydrochloride levels in human plasma using liquid chromatography with mass spectrometry (LC–MS/MS). Imeglimin, an oral antidiabetic medication, has demonstrated signif...

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Bibliographic Details
Main Authors: Chandni V. Chandarana, Vidhi H. Vashi, Anjana Bera, Jaiminkumar Patel
Format: Article
Language:English
Published: SpringerOpen 2025-06-01
Series:Future Journal of Pharmaceutical Sciences
Subjects:
Imeglimin hydrochloride
LC–MS/MS
Bioanalytical method validation
Human plasma
Diabetes
Online Access:https://doi.org/10.1186/s43094-025-00832-4
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