Marine bioactive peptides as potential therapeutic agents for wound healing – a review

Context Skin wounds resulting from dermatological diseases and other specific causes present significant challenges in health care. These wounds can lead to infections, chronic conditions, long-term complications and even mortality. Consequently, developing highly effective and viable therapies for...

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Main Authors: Kai Zheng, Ziwei Yang, Te Ba
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Annals of Medicine
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/07853890.2025.2530693
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author Kai Zheng
Ziwei Yang
Te Ba
author_facet Kai Zheng
Ziwei Yang
Te Ba
author_sort Kai Zheng
collection DOAJ
description Context Skin wounds resulting from dermatological diseases and other specific causes present significant challenges in health care. These wounds can lead to infections, chronic conditions, long-term complications and even mortality. Consequently, developing highly effective and viable therapies for wound healing is important. Marine bioactive peptides are increasingly being utilized because of their favourable biological properties, which include anti-inflammatory, antioxidant, antimicrobial, antiageing, antitumour and antihypertensive effects. These peptides offer several advantages, including high efficacy, excellent safety, clear target specificity and low allergenicity. Notably, scientific evidence has demonstrated that marine bioactive peptides promote skin injures repair and has underscored their substantial potential in wound healing.Objective Our objective is to provide molecular insights that may facilitate the development of innovative therapeutic agents aimed at improving wound healing and skin repair.Materials & methods This review synthesizes information from major databases, including ScienceDirect, Google Scholar, Scopus, PubMed and Springer Link. Publications were selected without date restrictions and used terms such as skin injures, wound healing, marine bioactive peptides, antimicrobial, ceRNA. Articles related to agriculture, ecology, or synthetic work or those published in languages other than English were excluded.Results and conclusions In this review, we integrated and examined the current understanding of wound care. Additionally, we analysed the underlying molecular mechanisms involved to elucidate the characteristics of marine bioactive peptides.
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spelling doaj-art-3d952098f89f4a87b3f81ef1a9c406e52025-07-13T14:30:33ZengTaylor & Francis GroupAnnals of Medicine0785-38901365-20602025-12-0157110.1080/07853890.2025.2530693Marine bioactive peptides as potential therapeutic agents for wound healing – a reviewKai Zheng0Ziwei Yang1Te Ba2Department of Burn Surgery, The Third Affiliated Hospital of Inner Mongolia Medical University (Inner Mongolia Bao Gang Hospital), Baotou, ChinaDepartment of Burn Surgery, The Third Affiliated Hospital of Inner Mongolia Medical University (Inner Mongolia Bao Gang Hospital), Baotou, ChinaDepartment of Burn Surgery, The Third Affiliated Hospital of Inner Mongolia Medical University (Inner Mongolia Bao Gang Hospital), Baotou, ChinaContext Skin wounds resulting from dermatological diseases and other specific causes present significant challenges in health care. These wounds can lead to infections, chronic conditions, long-term complications and even mortality. Consequently, developing highly effective and viable therapies for wound healing is important. Marine bioactive peptides are increasingly being utilized because of their favourable biological properties, which include anti-inflammatory, antioxidant, antimicrobial, antiageing, antitumour and antihypertensive effects. These peptides offer several advantages, including high efficacy, excellent safety, clear target specificity and low allergenicity. Notably, scientific evidence has demonstrated that marine bioactive peptides promote skin injures repair and has underscored their substantial potential in wound healing.Objective Our objective is to provide molecular insights that may facilitate the development of innovative therapeutic agents aimed at improving wound healing and skin repair.Materials & methods This review synthesizes information from major databases, including ScienceDirect, Google Scholar, Scopus, PubMed and Springer Link. Publications were selected without date restrictions and used terms such as skin injures, wound healing, marine bioactive peptides, antimicrobial, ceRNA. Articles related to agriculture, ecology, or synthetic work or those published in languages other than English were excluded.Results and conclusions In this review, we integrated and examined the current understanding of wound care. Additionally, we analysed the underlying molecular mechanisms involved to elucidate the characteristics of marine bioactive peptides.https://www.tandfonline.com/doi/10.1080/07853890.2025.2530693Wound healingskin injuriesmarine peptidesantimicrobial peptidesceRNA network
spellingShingle Kai Zheng
Ziwei Yang
Te Ba
Marine bioactive peptides as potential therapeutic agents for wound healing – a review
Annals of Medicine
Wound healing
skin injuries
marine peptides
antimicrobial peptides
ceRNA network
title Marine bioactive peptides as potential therapeutic agents for wound healing – a review
title_full Marine bioactive peptides as potential therapeutic agents for wound healing – a review
title_fullStr Marine bioactive peptides as potential therapeutic agents for wound healing – a review
title_full_unstemmed Marine bioactive peptides as potential therapeutic agents for wound healing – a review
title_short Marine bioactive peptides as potential therapeutic agents for wound healing – a review
title_sort marine bioactive peptides as potential therapeutic agents for wound healing a review
topic Wound healing
skin injuries
marine peptides
antimicrobial peptides
ceRNA network
url https://www.tandfonline.com/doi/10.1080/07853890.2025.2530693
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AT ziweiyang marinebioactivepeptidesaspotentialtherapeuticagentsforwoundhealingareview
AT teba marinebioactivepeptidesaspotentialtherapeuticagentsforwoundhealingareview