Generation of a Bartter syndrome type 3 patient-derived induced pluripotent stem cell line ISRM-BS3-UM18-iPSC (HHUUKDi014-A)

Generation of a Bartter syndrome type 3 patient-derived induced pluripotent stem cell line ISRM-BS3-UM18-iPSC (HHUUKDi014-A)

SIX2-positive urine-derived renal progenitor cells (UdRPCs) were isolated from an 18-year-old Bartter syndrome type 3 (BS3) patient within a homozygous CLCNKB gene deletion. Two episomal-based plasmids expressing OCT4, SOX2, NANOG, KLF4, c-MYC and LIN28 we were able to generate an integration-free i...

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Main Authors: Chantelle Thimm, Chutong Zhong, Wasco Wruck, Alessandra Grillo, Rosanne Mack, Martina Bohndorf, Nina Graffmann, Anson Tang, Viola D’Ambrosio, Elizabeth R Wan, Keith Siew, Rhys D Evans, Stephan B. Walsh, James Adjaye
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506125001102
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