Efficacy of Topical Andrographis Paniculata Extract for Pruritus in Chronic Liver Disease: A Randomized, Placebo-Controlled Trial

QR Code

Efficacy of Topical Andrographis Paniculata Extract for Pruritus in Chronic Liver Disease: A Randomized, Placebo-Controlled Trial

Objective: Assessing the effectiveness of topical extract from Andrographis paniculata, which has anti-inflammatory properties, in reducing pruritus in individuals with chronic liver disease. Materials and Methods: At Chiang Rai Prachanukroh Hospital, a randomized, placebo-controlled trial was ca...

Full description

Saved in:

Bibliographic Details
Main Authors:	Chotipong Siripipattanamongkol, Vich Thampanya, Piyaporn Sirijanchune, Nonlawan Chueamuangphan, Watcharee Khunkitti
Format:	Article
Language:	English
Published:	Faculty of Medicine Siriraj Hospital 2025-07-01
Series:	Siriraj Medical Journal
Subjects:	Andrographis paniculata pruritus quality of life chronic liver disease topical treatment
Online Access:	https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/273826
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Anticonvulsant Activity of Aqueous Extract of Andrographis paniculata Leaves in Wistar Albino Rats
by: M S Umamageswari, et al.
Published: (2025-07-01)

Effects of Andrographis paniculata Leaf Extract on C-Reactive Protein and Serum Ferritin in Lipopolysaccharide-Induced Sepsis Model Rat
by: Rezya Salsabela, et al.
Published: (2023-05-01)

Supplementation of Sambiloto (Andrographis paniculata) Leaf Flour through Broiler Drinking Water against Antibody Titers of Newcastle Disease, Avian Influenza, and Infectious Bursal Disease
by: Mia Widowati, et al.
Published: (2022-03-01)

Exploring the clinical effects of Andrographis paniculata-derived compounds, its extract, or derivatives for the treatment of COVID-19: a systematic review and meta-analysis
by: Peerapong Prabhakornritta, et al.
Published: (2025-07-01)

Pruritus in Uremic Patients: Approaches to Alleviating a Common Symptom in Chronic Kidney Disease
by: Ștefania Cîrstea, et al.
Published: (2025-06-01)

The research of the <em>Phlox paniculata </em>L. flowering biological features
by: A. I. Sokolkina, et al.
Published: (2024-10-01)

Insomnia, pruritus, and constipation in hemodialysis patients: a cross-sectional study
by: Jing Zhu, et al.
Published: (2025-08-01)

Variation in Management of CKD-Associated Pruritus: Results From a Multinational Survey of Kidney Units
by: Sreeram Venugopal, et al.
Published: (2025-07-01)

Pruritus and Atopic Dermatitis: from Etiological Features to Management
by: Nikolay N. Murashkin, et al.
Published: (2020-12-01)

Psoriasis associated with pruritus: variability of clinical manifestations spectrum, correlation analysis of psychopathological symptoms and their impact on quality of life
by: H. I. Makurina, et al.
Published: (2025-06-01)

An Indole-Rich Postbiotic Reduces Itching in Dogs: A Randomized, Double-Blinded Placebo-Controlled Study
by: Aylesse Sordillo, et al.
Published: (2025-07-01)

Chronic Kidney Disease-Associated Pruritus in Patients Undergoing Haemodialysis—A Cross-Sectional Study
by: Teng Wang, et al.
Published: (2025-05-01)

The High Correlation Between Survey Assessments for Chronic Kidney Disease-Associated Pruritus, and Its Associations with Clinical Outcomes
by: Huei Hsun Wen, et al.
Published: (2025-04-01)

Study of Th1/Th2 cytokine balance status in patients with generalized pruritus
by: YU Hai-yan, et al.
Published: (2004-03-01)

The Severity, Quality of Life, and Correlated Factors of Chronic Kidney Disease-associated Pruritus between Hemodialysis and Kidney Transplant Patients: A Cross-sectional Study
by: Melody Febriana Andardewi, et al.
Published: (2024-07-01)

Assessment of Efficacy of Adjuvant Topical Rituximab Encapsulated in Nanoparticle Gel in Oral Pemphigus Vulgaris: A Randomized, Double-Blind, Placebo-Controlled, Pilot Study
by: Pratik Rajendra Mohta, et al.
Published: (2025-07-01)

A Clinicomycological Analysis of Fungi Involved in Otomycosis
by: Dianitta Devapriya Veronica
Published: (2025-08-01)

Andrographis paniculata (Burm.f) Wall. ex Ness: A Potent Antibacterial Plant
by: Ahmed, Qamar Uddin, et al.
Published: (2012)

Chemopreventive efficacy of Andrographis paniculata on azoxymethane-induced aberrant colon crypt foci in vivo.
by: Nawal Al-Henhena, et al.
Published: (2014-01-01)

Retraction: Chemopreventive efficacy of Andrographis paniculata on Azoxymethane-induced aberrant colon crypt foci In Vivo.
by: PLOS One Editors
Published: (2025-01-01)

Retraction: Chemopreventive efficacy of Andrographis paniculata on Azoxymethane-induced aberrant colon crypt foci In Vivo
Published: (2025-01-01)

Physio-agronomic characteristics and andrographolide yield of Andrographis paniculata in response to endophytic Bacillus sp and phosphorus
by: Gusmaini Gusmaini, et al.
Published: (2025-07-01)

Effect of Fermentation Duration on the Chemical Characteristics and Antioxidant Activity of Sambiloto Leaf (Andrographis paniculata) Kombucha
by: Tri Diansy Yana Purwono, et al.
Published: (2025-06-01)

Clinical Presentation and Diagnosis of Multisystemic Eosinophilic Epitheliotropic Disease in a Miniature Donkey: A Case Report
by: Carla K. Enriquez, et al.
Published: (2025-07-01)

Method of Syntactic Analysis of Chinese Sentences on Topical Components
by: K. E. Kotcik
Published: (2018-10-01)

Mapping Russian International Relations: A Topic Modelling Approach
by: I. Khludov, et al.
Published: (2024-09-01)

Predictors of Topical Corticosteroid Adherence Among Caregivers of Children with Atopic Eczema
by: Liew ELF, et al.
Published: (2025-05-01)

FROM TOPIC SELECTION TO SUCCESSFUL PUBLICATION: A ROADMAP FOR PHILOSOPHY DOCTOR (PHD) SUPERVISORS AND STUDENTS
by: Burhan Fatih Kocyigit, et al.
Published: (2025-06-01)

Onychodystrophies: possibilities of topical therapy
by: Irena L. Shlivko, et al.
Published: (2025-06-01)

Research on the hysteresis effect of topic related evolution for emerging trends prediction
by: Liu Ziqiang, et al.
Published: (2025-04-01)

The Topicality and the Utility of the Teachings of the Holy Fathers
by: Liviu Petcu
Published: (2017-05-01)

WordMap: Text Mining Application of Enhanced Corpus Segmentation and Semantic Topic Recognition
by: Zhijian Wei, et al.
Published: (2025-06-01)

Prurigo Nodularis in a Patient With Primary B‐Cell Immunodeficiency Successfully Treated With Low‐Dose Methotrexate: A Case Report
by: Hamad El Hajj, et al.
Published: (2025-07-01)

Leveraging Topic Features in Prediction of Social Network Community Evolutions
by: Rahman Nahi Abid, et al.
Published: (2025-01-01)

Traffic Scene Analysis using Hierarchical Sparse Topical Coding
by: P. Ahmadi, et al.
Published: (2018-12-01)

Comparative Study of Antimalarial Effect of Sambiloto (Andrographis paniculata) Extract, Chloroquine and Artemisinin and Their Combination Against Plasmodium falciparum In-vitro
by: Umar Zein, et al.
Published: (2013-01-01)

A Comparison of the Direct Compression Characteristics of Andrographis paniculata, Eurycoma longifolia Jack, and Orthosiphon stamineus Extracts for Tablet Development
by: Yusof, Yus Aniza, et al.
Published: (2011)

Comparative Study of Antimalarial Effect of Sambiloto (Andrographis paniculata) Extract, Chloroquine and Artemisinin and Their Combination Against Plasmodium falciparum In-vitro
by: Umar Zein, et al.
Published: (2013-01-01)

Comparative Study of Antimalarial Effect of Sambiloto (Andrographis paniculata) Extract, Chloroquine and Artemisinin and Their Combination Against Plasmodium falciparum In-vitro
by: Umar Zein, et al.
Published: (2013-01-01)

THE EFFICACY OF TOPICAL CLINDAMYCIN GEL ON SEVERITY DEGREE OF ACNE VULGARIS AMONG FEMALE COLLEGE STUDENTS
by: Rani Puspita Hapsari, et al.
Published: (2020-06-01)