ANTIDIABETIC ACTIVITY OF GUANIDINIUM SALT 2-AMINOPHENYLACETATE
The purpose of the real research was studying of antidiabetic activity of new products of organic synthesis - guanidinium salt 2-aminophenylacetate. It was detected a pronounced hypoglycemic effect of the compounds when administered in intact animals and animals with alloxan diabetes model, and show...
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| Format: | Article |
| Language: | Russian |
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LLC Center of Pharmaceutical Analytics (LLC «CPHA»)
2019-01-01
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| Series: | Разработка и регистрация лекарственных средств |
| Subjects: | |
| Online Access: | https://www.pharmjournal.ru/jour/article/view/237 |
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| _version_ | 1839586777610846208 |
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| author | E. V. Ponomarenko |
| author_facet | E. V. Ponomarenko |
| author_sort | E. V. Ponomarenko |
| collection | DOAJ |
| description | The purpose of the real research was studying of antidiabetic activity of new products of organic synthesis - guanidinium salt 2-aminophenylacetate. It was detected a pronounced hypoglycemic effect of the compounds when administered in intact animals and animals with alloxan diabetes model, and shows that the studied compound exhibits antiadrenergic effect and potentiates the effect of exogenous insulin. |
| format | Article |
| id | doaj-art-3cb60c8344e34fde8eb0e62a9ee6cdf2 |
| institution | Matheson Library |
| issn | 2305-2066 2658-5049 |
| language | Russian |
| publishDate | 2019-01-01 |
| publisher | LLC Center of Pharmaceutical Analytics (LLC «CPHA») |
| record_format | Article |
| series | Разработка и регистрация лекарственных средств |
| spelling | doaj-art-3cb60c8344e34fde8eb0e62a9ee6cdf22025-08-03T19:23:53ZrusLLC Center of Pharmaceutical Analytics (LLC «CPHA»)Разработка и регистрация лекарственных средств2305-20662658-50492019-01-0101172175237ANTIDIABETIC ACTIVITY OF GUANIDINIUM SALT 2-AMINOPHENYLACETATEE. V. Ponomarenko0State Budgetary Educational Institution of Higher Professional Education «Perm State Pharmaceutical Academy» of the Ministry of health of the Russian FederationThe purpose of the real research was studying of antidiabetic activity of new products of organic synthesis - guanidinium salt 2-aminophenylacetate. It was detected a pronounced hypoglycemic effect of the compounds when administered in intact animals and animals with alloxan diabetes model, and shows that the studied compound exhibits antiadrenergic effect and potentiates the effect of exogenous insulin.https://www.pharmjournal.ru/jour/article/view/237antidiabetic activityantiadrenergic effecthypoglycemic effect |
| spellingShingle | E. V. Ponomarenko ANTIDIABETIC ACTIVITY OF GUANIDINIUM SALT 2-AMINOPHENYLACETATE Разработка и регистрация лекарственных средств antidiabetic activity antiadrenergic effect hypoglycemic effect |
| title | ANTIDIABETIC ACTIVITY OF GUANIDINIUM SALT 2-AMINOPHENYLACETATE |
| title_full | ANTIDIABETIC ACTIVITY OF GUANIDINIUM SALT 2-AMINOPHENYLACETATE |
| title_fullStr | ANTIDIABETIC ACTIVITY OF GUANIDINIUM SALT 2-AMINOPHENYLACETATE |
| title_full_unstemmed | ANTIDIABETIC ACTIVITY OF GUANIDINIUM SALT 2-AMINOPHENYLACETATE |
| title_short | ANTIDIABETIC ACTIVITY OF GUANIDINIUM SALT 2-AMINOPHENYLACETATE |
| title_sort | antidiabetic activity of guanidinium salt 2 aminophenylacetate |
| topic | antidiabetic activity antiadrenergic effect hypoglycemic effect |
| url | https://www.pharmjournal.ru/jour/article/view/237 |
| work_keys_str_mv | AT evponomarenko antidiabeticactivityofguanidiniumsalt2aminophenylacetate |