ANTIDIABETIC ACTIVITY OF GUANIDINIUM SALT 2-AMINOPHENYLACETATE

The purpose of the real research was studying of antidiabetic activity of new products of organic synthesis - guanidinium salt 2-aminophenylacetate. It was detected a pronounced hypoglycemic effect of the compounds when administered in intact animals and animals with alloxan diabetes model, and show...

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Bibliographic Details
Main Author: E. V. Ponomarenko
Format: Article
Language:Russian
Published: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2019-01-01
Series:Разработка и регистрация лекарственных средств
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Online Access:https://www.pharmjournal.ru/jour/article/view/237
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Summary:The purpose of the real research was studying of antidiabetic activity of new products of organic synthesis - guanidinium salt 2-aminophenylacetate. It was detected a pronounced hypoglycemic effect of the compounds when administered in intact animals and animals with alloxan diabetes model, and shows that the studied compound exhibits antiadrenergic effect and potentiates the effect of exogenous insulin.
ISSN:2305-2066
2658-5049