Double Proteolysis for N- and O-glycan Analysis of Fc-fusion Protein Etanercept

Introduction. Highly glycosylated proteins are the most abundant class of modern biopharmaceuticals. A majority of such therapeuticals produced by Russian biopharmaceutical companies is biosimilars. The foundation of biosimilar manufacturing is analytical assessment of structure equivalence to an or...

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Bibliographic Details
Main Authors: V. G. Varzieva, N. V. Mesonzhnik, A. О. Belushenko, N. L. Bochkareva, S. А. Appolonova
Format: Article
Language:Russian
Published: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2023-02-01
Series:Разработка и регистрация лекарственных средств
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Online Access:https://www.pharmjournal.ru/jour/article/view/1440
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