Osteopontin promotes rat hepatocyte proliferation both in vitro and in vivo

Osteopontin promotes rat hepatocyte proliferation both in vitro and in vivo

Aim This study aimed to examine the effects of osteopontin (OPN) on hepatocyte growth and liver regeneration (LR).Methods A recombinant lentivirus expressing OPN and OPN-siRNAs were used to treat BRL-3A cells, while the adenovirus expressing OPN or OPN-targeted shRNA were applied for rat primary hep...

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Bibliographische Detailangaben
Hauptverfasser: Gaiping Wang, Peipei Chu, Meng Chen, Liya Cheng, Congcong Zhao, Shasha Chen, Xiaofang Li, Ganggang Yang, Cuifang Chang
Format: Artikel
Sprache:Englisch
Veröffentlicht: Taylor & Francis Group 2019-12-01
Schriftenreihe:Artificial Cells, Nanomedicine, and Biotechnology
Schlagworte:
Osteopontin
BRL-3A
primary hepatocyte
hepatocyte proliferation
liver regeneration
Online-Zugang:https://www.tandfonline.com/doi/10.1080/21691401.2019.1666862
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