Expression of Slitrk6 during testicular tissue development in rats
Objective To investigate the transcriptional and translational expression of Slitrk6 in rat spermatogenesis. Methods The mRNA transcription level and translation level of Slitrk6 were detected by RT-qPCR and Western blot, respectively in testis of rats aged 2-65 days (repeat three times at each time...
Saved in:
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | Chinese |
| Published: |
Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.
2025-07-01
|
| Series: | Jichu yixue yu linchuang |
| Subjects: | |
| Online Access: | https://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2025-45-7-912.pdf |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | Objective To investigate the transcriptional and translational expression of Slitrk6 in rat spermatogenesis. Methods The mRNA transcription level and translation level of Slitrk6 were detected by RT-qPCR and Western blot, respectively in testis of rats aged 2-65 days (repeat three times at each time point). Results The mRNA expression of Slitrk6 reached the highest on day 4 and day 10. SLITRK6 protein was continuously expressed during testis development in rats. Slitrk6 was found in human testis through PPI network. Conclusions Slitrk6 is potentially involved in mitosis and meiosis in spermatogenesis; The Slitrk6 may be one of the key genes in spermatogenesis. SLITRK6 protein is involved in mitosis and the transformation of round spermatids.The results lay a foundation for subsequent research on male infertility. |
|---|---|
| ISSN: | 1001-6325 |