Pharmacokinetics and exposure–safety relationship of ciprofol for sedation in mechanically ventilated patients in the intensive care unit

Abstract Ciprofol (HSK3486) is a newly developed, highly selective γ‐aminobutyric acid‐A (GABAA) receptor potentiator that is recently approved for a new indication of sedation for patients in the intensive care unit (ICU) in China. This analysis aimed to characterize the population pharmacokinetics...

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Bibliographic Details
Main Authors: Lu Liu, Kun Wang, Zhongyi Sun, Pangke Yan, Mengyue Hu, Xiao Liu, Meixia Chen, Nan Wu, Xiaoqiang Xiang
Format: Article
Language:English
Published: Wiley 2024-05-01
Series:CPT: Pharmacometrics & Systems Pharmacology
Online Access:https://doi.org/10.1002/psp4.13121
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