Therapeutic potential of magnesium sulfate in improving duodenal homeobox 1 and PPARG coactivator 1 alpha genes to reduce pancreatic insulin resistance in F1 offspring of diabetic rats

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Therapeutic potential of magnesium sulfate in improving duodenal homeobox 1 and PPARG coactivator 1 alpha genes to reduce pancreatic insulin resistance in F1 offspring of diabetic rats

Objective(s): The study aimed to investigate the role of magnesium sulfate (MgSO4) therapy in pancreatic insulin resistance (IR) in diabetic and non-diabetic rats and their F1 offspring following administration of a high-fat diet (HFD). Materials and Methods: Diabetes was induced in the subjects thr...

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Bibliographic Details
Main Authors:	Mahtab Ghanbari Rad, Hossein Rezazadeh, Mohammadreza Sharifi, Nepton Soltani
Format:	Article
Language:	English
Published:	Mashhad University of Medical Sciences 2025-09-01
Series:	Iranian Journal of Basic Medical Sciences
Subjects:	diabetes euglycemic - hyperinsulinemic clamp insulin resistance magnesium
Online Access:	https://ijbms.mums.ac.ir/article_26112_185e506aa8eedc9f0aa83cd4ed49003c.pdf
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