Synthesis of Azide-Labeled β-Lactosylceramide Analogs Containing Different Lipid Chains as Useful Glycosphingolipid Probes

Synthesis of Azide-Labeled β-Lactosylceramide Analogs Containing Different Lipid Chains as Useful Glycosphingolipid Probes

β-Lactosylceramide (β-LacCer) is not only a key intermediate in the biosynthesis of complex glycosphingolipids (GSLs) but also an important regulator of many biological processes. To facilitate the investigation of β-LacCer and other GSLs, a series of β-LacCer analogs with an azido group at the 6-&l...

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Bibliographic Details
Main Authors: Basant Mohamed, Rajendra Rohokale, Xin Yan, Amany M. Ghanim, Nermine A. Osman, Hanan A. Abdel-Fattah, Zhongwu Guo
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Molecules
Subjects:
carbohydrates
glycolipids
glycosphingolipids
β-Lactosylceramide
lipids
lactose
Online Access:https://www.mdpi.com/1420-3049/30/13/2667
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