INTRATUMORAL AMPLIFICATION HETEROGENEITY IN HER2/neu-POSITIVE BREAST CANCER MOLECULAR-GENETIC SUBTYPES

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INTRATUMORAL AMPLIFICATION HETEROGENEITY IN HER2/neu-POSITIVE BREAST CANCER MOLECULAR-GENETIC SUBTYPES

The defining feature of HER2/neu-positive Luminal B and HER2/neu-positive (non-luminal) subtype breast cancer is HER2/neu gene amplification and protein overexpression on cancer cell membrane. The HER2-targeted therapy is nowadays available for patients with HER2-positive breast cancer However, a si...

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Bibliographic Details
Main Authors:	L. N. Vashchenko, L. E. Zavalishina, I. A. Pavlenko, P. E. Povilaitite
Format:	Article
Language:	Russian
Published:	Russian Academy of Sciences, Siberian Branch Publishing House 2019-11-01
Series:	Сибирский научный медицинский журнал
Subjects:	breast cancer intratumoral heterogeneity her2 gene amplification fluorescence in situ hybridization (fish) targeted therapy
Online Access:	https://sibmed.elpub.ru/jour/article/view/285
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