Drug-induced liver injury in cancer patients

Drug-induced liver injury in cancer patients

This review includes information about epidemiological data, development feature, phenotypes, principles of classification, diagnosis, and prognosis for drug-induced liver injury (DILI). Actual clinical recommendations regarding management of the DILI arising in the chemotherapy of cancer discussed....

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Bibliographic Details
Main Authors: V. T. Ivashkin, K. L. Raikhelson, L. K. Palgova, M. V. Maevskaya, O. A. Gerasimova, E. A. Kondrashina, N. V. Marchenko, A. Yu. Baranovsky
Format: Article
Language:Russian
Published: ABV-press 2020-10-01
Series:Онкогематология
Subjects:
drug-induced liver injury
hepatotoxicity
cancer
chemotherapy
checkpoint inhibitor
n-acetylcysteine
glucocorticosteroids
s-аdenosylmethionine
bicyclol
essential phospholipid
Online Access:https://oncohematology.abvpress.ru/ongm/article/view/434
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Summary:This review includes information about epidemiological data, development feature, phenotypes, principles of classification, diagnosis, and prognosis for drug-induced liver injury (DILI). Actual clinical recommendations regarding management of the DILI arising in the chemotherapy of cancer discussed. Drugs that can influence on individual pathogenetic mechanisms of growth and symptoms DILI are considered. Clinical studies for the prophylaxis and treatment of DILI associated with anticancer chemotherapy analyzed in detail. The prevention and treatment regimens for DILI in patients receiving chemotherapy and immunotherapy various localizations of cancer given both in research and in practical recommendations.
ISSN:1818-8346
2413-4023

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