RIDDEN: Data-driven inference of receptor activity from transcriptomic data.
Intracellular signaling initiated from ligand-bound receptors plays a fundamental role in both physiological regulation and development of disease states, making receptors one of the most frequent drug targets. Systems level analysis of receptor activity can help to identify cell and disease type-sp...
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Main Authors: | Szilvia Barsi, Eszter Varga, Daniel Dimitrov, Julio Saez-Rodriguez, László Hunyady, Bence Szalai |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2025-06-01
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Series: | PLoS Computational Biology |
Online Access: | https://doi.org/10.1371/journal.pcbi.1013188 |
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