Development of Spectrophotometric method for quantitative determination of dexamethasone in pharmaceutical preparations

This Study is concerned a fast, easy, sensitive, accurate and economical spectrophotometric method for the determination of Dexamethasone. This method based on the use of UV- spectra measurements at 242 nm.  The linearity of the method is performed between (3 - 65) μg.ml-1, the  coefficient of ...

Full description

Saved in:
Bibliographic Details
Main Authors: Rafal Abdulraheem Abdullah, Khalaf F. AL-Samarraee
Format: Article
Language:English
Published: Tikrit University 2023-01-01
Series:Tikrit Journal of Pure Science
Subjects:
Online Access:https://tjpsj.org/index.php/tjps/article/view/777
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:This Study is concerned a fast, easy, sensitive, accurate and economical spectrophotometric method for the determination of Dexamethasone. This method based on the use of UV- spectra measurements at 242 nm.  The linearity of the method is performed between (3 - 65) μg.ml-1, the  coefficient of  correlation was = 0.9998. The value of Rec% and RSD% are found at the range (95.28 -102.86)% and (0 - 0.272 )% respectively, The LOD and LOQ were (0.024and 0.081) μg.ml-1, respectively . The method was successfully applied to the determination of DMT in Bulk and pharmaceutical preparations
ISSN:1813-1662
2415-1726