Natural active botanical metabolites: targeting AMPK signaling pathway to treat metabolic dysfunction-associated fatty liver disease

Natural active botanical metabolites: targeting AMPK signaling pathway to treat metabolic dysfunction-associated fatty liver disease

Metabolic dysfunction-associated fatty liver disease (MAFLD), also known as non-alcoholic fatty liver disease (NAFLD), has emerged as one of the most common chronic liver diseases globally, with a tendency to progress gradually. With persistent disease progression, it may subsequently manifest as co...

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Bibliographic Details
Main Authors: Hualing Wang, Xinyu Liu, Chunyi Wang, Shishuang Yu, Xiuli Yang, Xiyu Cao, Maocai Luo, Shiwei Liu, Chuantao Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Pharmacology
Subjects:
metabolic dysfunction-associated fatty liver disease
AMPK
natural active botanical metabolites
lipid metabolism
de novo lipogenesis
fatty acid oxidation
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1611400/full
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