The effect of recombinant interleukin-2 on the variation of the cytokine balance in the patients with uterine myomas

Purpose: To develop an option for the anesthetic support of such surgical interventions with the use of human recombinant interleukin-2, which makes it possible to normalize the cytokine balance of the patients with uterine myomas during the surgical stress and in the early post-operative period.Mat...

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Bibliographic Details
Main Authors: I. N. Pyatakova, V. M. Zhenilo
Format: Article
Language:English
Published: State Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian Federation 2010-03-01
Series:Медицинский вестник Юга России
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Online Access:https://www.medicalherald.ru/jour/article/view/1286
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Summary:Purpose: To develop an option for the anesthetic support of such surgical interventions with the use of human recombinant interleukin-2, which makes it possible to normalize the cytokine balance of the patients with uterine myomas during the surgical stress and in the early post-operative period.Materials and Methods: The cytokine balance was measured during the surgery and in the early post-operative period in patients with uterine myomas operated on with total intravenous anesthesia and artificial ventilation of the lungs.Results: Based on a solid-phase immunoenzymatic test, it was found that at all stages of examination of that group of patients there was an imbalance between the pro-inflammatory and the anti-inflammatory links of the cytokine regulation of the course of the adaptation processes.
ISSN:2219-8075
2618-7876