Prevention and correction of hypocalaemia during systematic hypothermia in patients with aneurismal subarachnoid hemorrhages.

The effectiveness of hypothermia as a method of neuroprotection in brain damage has been proved in many studies, but a large number of complications requires development of further protocols of its management. The article presents experience of treatment of aneurismal subarachnoid hemorrhage under c...

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Main Author: S. Dudukina
Format: Article
Language:English
Published: Dnipro State Medical University 2013-10-01
Series:Medičnì Perspektivi
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Online Access:https://journals.uran.ua/index.php/2307-0404/article/view/18944
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author S. Dudukina
author_facet S. Dudukina
author_sort S. Dudukina
collection DOAJ
description The effectiveness of hypothermia as a method of neuroprotection in brain damage has been proved in many studies, but a large number of complications requires development of further protocols of its management. The article presents experience of treatment of aneurismal subarachnoid hemorrhage under conditions of preventive hypothermia. 84 patients were examined. In 56 of them the efficacy of developed method on prevention and correction of hypocalaemia developed as a result of cold diuresis has been proposed. It has been found that decrease in plasma potassium occurs in parallel with decrease in body temperature regardless the technique of potassium chloride injection. Introduction of potassium chloride solution in physiological dose of 0.2 mmol/kg prevents hypocalaemia development during preventive hypothermia. Injection of potassium chloride in the physiological dose of 0.2 mmol/kg/h and after beginning of patient’s rewarming – 0.8 mmol/kg within the period of one postsurgery day prevents the development of postoperative hypocalaemia in the postoperative period; and after patient’s rewarming– 0.8. mmol/kg within the period of one postoperative day prevents development of postoperative cardiac complications in the perioperative period by 20%.
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spelling doaj-art-34e4a33dc7bb4b058194974d2bcb4dfa2025-06-27T10:24:14ZengDnipro State Medical UniversityMedičnì Perspektivi2307-04042786-48042013-10-0118310.26641/2307-0404.2013.3.18944Prevention and correction of hypocalaemia during systematic hypothermia in patients with aneurismal subarachnoid hemorrhages.S. Dudukina0Dnipropetrovs’k Regional HospitalThe effectiveness of hypothermia as a method of neuroprotection in brain damage has been proved in many studies, but a large number of complications requires development of further protocols of its management. The article presents experience of treatment of aneurismal subarachnoid hemorrhage under conditions of preventive hypothermia. 84 patients were examined. In 56 of them the efficacy of developed method on prevention and correction of hypocalaemia developed as a result of cold diuresis has been proposed. It has been found that decrease in plasma potassium occurs in parallel with decrease in body temperature regardless the technique of potassium chloride injection. Introduction of potassium chloride solution in physiological dose of 0.2 mmol/kg prevents hypocalaemia development during preventive hypothermia. Injection of potassium chloride in the physiological dose of 0.2 mmol/kg/h and after beginning of patient’s rewarming – 0.8 mmol/kg within the period of one postsurgery day prevents the development of postoperative hypocalaemia in the postoperative period; and after patient’s rewarming– 0.8. mmol/kg within the period of one postoperative day prevents development of postoperative cardiac complications in the perioperative period by 20%.https://journals.uran.ua/index.php/2307-0404/article/view/18944subarachnoid hemorrhagepreventivehypothermia hypocalaemiacardiological complications
spellingShingle S. Dudukina
Prevention and correction of hypocalaemia during systematic hypothermia in patients with aneurismal subarachnoid hemorrhages.
Medičnì Perspektivi
subarachnoid hemorrhage
preventive
hypothermia hypocalaemia
cardiological complications
title Prevention and correction of hypocalaemia during systematic hypothermia in patients with aneurismal subarachnoid hemorrhages.
title_full Prevention and correction of hypocalaemia during systematic hypothermia in patients with aneurismal subarachnoid hemorrhages.
title_fullStr Prevention and correction of hypocalaemia during systematic hypothermia in patients with aneurismal subarachnoid hemorrhages.
title_full_unstemmed Prevention and correction of hypocalaemia during systematic hypothermia in patients with aneurismal subarachnoid hemorrhages.
title_short Prevention and correction of hypocalaemia during systematic hypothermia in patients with aneurismal subarachnoid hemorrhages.
title_sort prevention and correction of hypocalaemia during systematic hypothermia in patients with aneurismal subarachnoid hemorrhages
topic subarachnoid hemorrhage
preventive
hypothermia hypocalaemia
cardiological complications
url https://journals.uran.ua/index.php/2307-0404/article/view/18944
work_keys_str_mv AT sdudukina preventionandcorrectionofhypocalaemiaduringsystematichypothermiainpatientswithaneurismalsubarachnoidhemorrhages