Department of pathological physiology
It is known that as long as antinociceptive system functions adequately pain can develop as a component of different injuries. One of the most important mechanisms of antinociception – humoral that means production of substances that block pain transmission and formation of pain feeling. Humoral mec...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
State Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian Federation
2014-09-01
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| Series: | Медицинский вестник Юга России |
| Subjects: | |
| Online Access: | https://www.medicalherald.ru/jour/article/view/34 |
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| Summary: | It is known that as long as antinociceptive system functions adequately pain can develop as a component of different injuries. One of the most important mechanisms of antinociception – humoral that means production of substances that block pain transmission and formation of pain feeling. Humoral mechanism includes: opioid, monoaminergic (norepinephrine, dopamine, serotonin), cholinergic, GABAergic, cannabinoid and orexin systems. Inflow of pain impulses induces production and excretion of different chemical substances which forms analgesia in different levels of pain system. |
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| ISSN: | 2219-8075 2618-7876 |