The association of factor V leiden and prothrombin gene mutation and placenta-mediated pregnancy complications: a systematic review and meta-analysis of prospective cohort studies.

The association of factor V leiden and prothrombin gene mutation and placenta-mediated pregnancy complications: a systematic review and meta-analysis of prospective cohort studies.

<h4>Background</h4>Factor V Leiden (FVL) and prothrombin gene mutation (PGM) are common inherited thrombophilias. Retrospective studies variably suggest a link between maternal FVL/PGM and placenta-mediated pregnancy complications including pregnancy loss, small for gestational age, pre-...

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Bibliographic Details
Main Authors: Marc A Rodger, Marisol T Betancourt, Peter Clark, Pelle G Lindqvist, Donna Dizon-Townson, Joanne Said, Uri Seligsohn, Marc Carrier, Ophira Salomon, Ian A Greer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-06-01
Series:PLoS Medicine
Online Access:https://doi.org/10.1371/journal.pmed.1000292
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