Microwave-assisted optimization extraction for green chili paste and investigation of its alpha-glucosidase inhibitory activity with molecular docking and molecular dynamics simulation for anti-diabetic potential

Microwave-assisted optimization extraction for green chili paste and investigation of its alpha-glucosidase inhibitory activity with molecular docking and molecular dynamics simulation for anti-diabetic potential

Type 2 diabetes (T2D) is a growing global health concern, necessitating alternative therapeutic strategies to regulate postprandial glucose levels. α-Glucosidase inhibitors (AGIs) delay glucose absorption but are often associated with adverse effects. Plant-based AGIs offer promising alternatives wi...

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Bibliographic Details
Main Authors: Woorawee Inthachat, Natnicha Promyos, Uthaiwan Suttisansanee, Rungrat Chamchan, Sirinapa Thangsiri, Boonrat Chantong, Pornsiri Pitchakarn, Piya Temviriyanukul
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Journal of Agriculture and Food Research
Subjects:
α-glucosidase
Diabetes
Green chili paste
Molecular docking
Response surface methodology
Sustainability
Online Access:http://www.sciencedirect.com/science/article/pii/S2666154325005010
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