Rheumatic diseases in women: impact on pregnancy and neonatal health

Background. Rheumatic diseases are a large group of heterogeneous inflammatory and degenerative-metabolic diseases, characterized by systemic damage, covering all structures of connective tissue (joints, cartilage, bones, periarticular tissues), and also involve blood vessels, internal organs, skin...

Full description

Saved in:
Bibliographic Details
Main Author: N. A. Pekareva
Format: Article
Language:Russian
Published: Open Systems Publication 2025-02-01
Series:Лечащий Врач
Subjects:
Online Access:https://journal.lvrach.ru/jour/article/view/1353
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1839591320547491840
author N. A. Pekareva
author_facet N. A. Pekareva
author_sort N. A. Pekareva
collection DOAJ
description Background. Rheumatic diseases are a large group of heterogeneous inflammatory and degenerative-metabolic diseases, characterized by systemic damage, covering all structures of connective tissue (joints, cartilage, bones, periarticular tissues), and also involve blood vessels, internal organs, skin and mucous membranes, mainly with a systemic, not local, nature of damage. Most chronic rheumatic diseases occur in women, and the onset coincides with the peak of childbearing age (18-45 years). The number of women with rheumatic diseases planning to have children increases annually everywhere.Results. The study of pregnancy outcomes, children's health in the neonatal period and during follow-up observation was conducted in women with rheumatic diseases. Women with rheumatic diseases are more likely to have premature births or require operative delivery. Newborns have an increased frequency of pathologies, including prematurity, low gestational weight, intrauterine pneumonia, necrotizing enterocolitis, respiratory distress syndrome and cardiac arrhythmias such as bradycardia and atrioventricular blocks. Children born to women with rheumatic diseases have lower weight-for-height indicators and Apgar scores, as well as a high frequency of complications in the early neonatal period. The health of children at 1 year of life was characterized by the presence of predominantly functional disorders. The decision on breastfeeding should be made individually for each woman with rheumatic diseases.Conclusion. Women with rheumatic diseases planning pregnancy require comprehensive dynamic observation. It is critical to adapt the therapeutic strategy to control rheumatic diseases and minimize the impact of autoantibodies on the fetus.
format Article
id doaj-art-33a129878dba47fba99652f7c204364f
institution Matheson Library
issn 1560-5175
2687-1181
language Russian
publishDate 2025-02-01
publisher Open Systems Publication
record_format Article
series Лечащий Врач
spelling doaj-art-33a129878dba47fba99652f7c204364f2025-08-03T13:02:57ZrusOpen Systems PublicationЛечащий Врач1560-51752687-11812025-02-010271210.51793/OS.2025.28.2.0011336Rheumatic diseases in women: impact on pregnancy and neonatal healthN. A. Pekareva0National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V. I. KulakovBackground. Rheumatic diseases are a large group of heterogeneous inflammatory and degenerative-metabolic diseases, characterized by systemic damage, covering all structures of connective tissue (joints, cartilage, bones, periarticular tissues), and also involve blood vessels, internal organs, skin and mucous membranes, mainly with a systemic, not local, nature of damage. Most chronic rheumatic diseases occur in women, and the onset coincides with the peak of childbearing age (18-45 years). The number of women with rheumatic diseases planning to have children increases annually everywhere.Results. The study of pregnancy outcomes, children's health in the neonatal period and during follow-up observation was conducted in women with rheumatic diseases. Women with rheumatic diseases are more likely to have premature births or require operative delivery. Newborns have an increased frequency of pathologies, including prematurity, low gestational weight, intrauterine pneumonia, necrotizing enterocolitis, respiratory distress syndrome and cardiac arrhythmias such as bradycardia and atrioventricular blocks. Children born to women with rheumatic diseases have lower weight-for-height indicators and Apgar scores, as well as a high frequency of complications in the early neonatal period. The health of children at 1 year of life was characterized by the presence of predominantly functional disorders. The decision on breastfeeding should be made individually for each woman with rheumatic diseases.Conclusion. Women with rheumatic diseases planning pregnancy require comprehensive dynamic observation. It is critical to adapt the therapeutic strategy to control rheumatic diseases and minimize the impact of autoantibodies on the fetus.https://journal.lvrach.ru/jour/article/view/1353pregnancyrheumatic diseasepathologypremature birthfunctional disorders
spellingShingle N. A. Pekareva
Rheumatic diseases in women: impact on pregnancy and neonatal health
Лечащий Врач
pregnancy
rheumatic disease
pathology
premature birth
functional disorders
title Rheumatic diseases in women: impact on pregnancy and neonatal health
title_full Rheumatic diseases in women: impact on pregnancy and neonatal health
title_fullStr Rheumatic diseases in women: impact on pregnancy and neonatal health
title_full_unstemmed Rheumatic diseases in women: impact on pregnancy and neonatal health
title_short Rheumatic diseases in women: impact on pregnancy and neonatal health
title_sort rheumatic diseases in women impact on pregnancy and neonatal health
topic pregnancy
rheumatic disease
pathology
premature birth
functional disorders
url https://journal.lvrach.ru/jour/article/view/1353
work_keys_str_mv AT napekareva rheumaticdiseasesinwomenimpactonpregnancyandneonatalhealth