Absolute Configuration and Chiroptical Properties of Flexible Drug Avapritinib

<b>Background/Objective</b>: Avapritinib is an orally bioavailable tyrosine kinase inhibitor and was approved by the FDA in 2020 for gastrointestinal stromal tumor treatments. Although avapritinib is known to be chiral, its stereochemistry was initially established randomly. This study a...

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Bibliographic Details
Main Authors: Ya-Dong Yang, Chen Zhao, Liang-Peng Li, Yi-Xin Lv, Bei-Bei Yang, Xin Li, Ru Wang, Li Li
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Pharmaceuticals
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Online Access:https://www.mdpi.com/1424-8247/18/6/833
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