FOCAL CORTICAL DYSPLASIAS: CLINICAL AND ELECTRO-NEUROIMAGING CHARACTERISTICS
In spite of a notable advance made in epileptology, resistant epilepsies account for approximately 30 % of all forms of epilepsy particularly in patients with focal seizures. One of the main causes of therapy-resistant focal epilepsies is focal cortical dysplasias (FCD). This term was first introduc...
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| Format: | Article |
| Language: | Russian |
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ABV-press
2016-08-01
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| Series: | Русский журнал детской неврологии |
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| Online Access: | https://rjdn.abvpress.ru/jour/article/view/149 |
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| author | K. Yu. Mukhin |
| author_facet | K. Yu. Mukhin |
| author_sort | K. Yu. Mukhin |
| collection | DOAJ |
| description | In spite of a notable advance made in epileptology, resistant epilepsies account for approximately 30 % of all forms of epilepsy particularly in patients with focal seizures. One of the main causes of therapy-resistant focal epilepsies is focal cortical dysplasias (FCD). This term was first introduced by D. Taylor et al. in 1971. FCD belongs to abnormal cortical development. Among all abnormalities of cortical development, FCD in surgically treated children amounts to 75 %. FCD is the most common cause of resistant epilepsy in children and the most frequent reason for diagnosing cryptogenic focal epilepsy with intractable seizures. The author gives a detailed literature review dedicated to FCD as a cause of resistant epilepsy, including the classification and histologic characteristics of FCD, its clinical manifestations and prognosis, and approaches to medical and surgical treatments. |
| format | Article |
| id | doaj-art-31a6684980c8436d9b38f34bb0b9d14c |
| institution | Matheson Library |
| issn | 2073-8803 2412-9178 |
| language | Russian |
| publishDate | 2016-08-01 |
| publisher | ABV-press |
| record_format | Article |
| series | Русский журнал детской неврологии |
| spelling | doaj-art-31a6684980c8436d9b38f34bb0b9d14c2025-08-04T14:12:11ZrusABV-pressРусский журнал детской неврологии2073-88032412-91782016-08-0111282410.17650/2073-8803-2016-11-2-8-24117FOCAL CORTICAL DYSPLASIAS: CLINICAL AND ELECTRO-NEUROIMAGING CHARACTERISTICSK. Yu. Mukhin0Svt. Luka's Institute of Child Neurology and Epilepsy, MoscowIn spite of a notable advance made in epileptology, resistant epilepsies account for approximately 30 % of all forms of epilepsy particularly in patients with focal seizures. One of the main causes of therapy-resistant focal epilepsies is focal cortical dysplasias (FCD). This term was first introduced by D. Taylor et al. in 1971. FCD belongs to abnormal cortical development. Among all abnormalities of cortical development, FCD in surgically treated children amounts to 75 %. FCD is the most common cause of resistant epilepsy in children and the most frequent reason for diagnosing cryptogenic focal epilepsy with intractable seizures. The author gives a detailed literature review dedicated to FCD as a cause of resistant epilepsy, including the classification and histologic characteristics of FCD, its clinical manifestations and prognosis, and approaches to medical and surgical treatments.https://rjdn.abvpress.ru/jour/article/view/149epilepsyantiepileptic therapyfocal epilepsytreatment-resistant epilepsiesfocal cortical dysplasiasclassificationclinical manifestationsprognosismedical treatmentsurgical treatment |
| spellingShingle | K. Yu. Mukhin FOCAL CORTICAL DYSPLASIAS: CLINICAL AND ELECTRO-NEUROIMAGING CHARACTERISTICS Русский журнал детской неврологии epilepsy antiepileptic therapy focal epilepsy treatment-resistant epilepsies focal cortical dysplasias classification clinical manifestations prognosis medical treatment surgical treatment |
| title | FOCAL CORTICAL DYSPLASIAS: CLINICAL AND ELECTRO-NEUROIMAGING CHARACTERISTICS |
| title_full | FOCAL CORTICAL DYSPLASIAS: CLINICAL AND ELECTRO-NEUROIMAGING CHARACTERISTICS |
| title_fullStr | FOCAL CORTICAL DYSPLASIAS: CLINICAL AND ELECTRO-NEUROIMAGING CHARACTERISTICS |
| title_full_unstemmed | FOCAL CORTICAL DYSPLASIAS: CLINICAL AND ELECTRO-NEUROIMAGING CHARACTERISTICS |
| title_short | FOCAL CORTICAL DYSPLASIAS: CLINICAL AND ELECTRO-NEUROIMAGING CHARACTERISTICS |
| title_sort | focal cortical dysplasias clinical and electro neuroimaging characteristics |
| topic | epilepsy antiepileptic therapy focal epilepsy treatment-resistant epilepsies focal cortical dysplasias classification clinical manifestations prognosis medical treatment surgical treatment |
| url | https://rjdn.abvpress.ru/jour/article/view/149 |
| work_keys_str_mv | AT kyumukhin focalcorticaldysplasiasclinicalandelectroneuroimagingcharacteristics |