Identification of an immunodominant region on a group A Streptococcus T-antigen reveals temperature-dependent motion in pili

Identification of an immunodominant region on a group A Streptococcus T-antigen reveals temperature-dependent motion in pili

Group A Streptococcus (GAS) is a globally important pathogen causing a broad range of human diseases. GAS pili are elongated proteins with a backbone comprised repeating T-antigen subunits, which extend from the cell surface and have important roles in adhesion and establishing infection. No GAS vac...

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Bibliographic Details
Main Authors: Jeremy M. Raynes, Paul G. Young, Natalie Lorenz, Jacelyn M.S. Loh, Reuben McGregor, Edward N. Baker, Thomas Proft, Nicole J. Moreland
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Virulence
Subjects:
Streptococcus pyogenes
T-antigen
pilus
antibody
temperature
motion
Online Access:https://www.tandfonline.com/doi/10.1080/21505594.2023.2180228
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https://www.tandfonline.com/doi/10.1080/21505594.2023.2180228

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