Cholemic Nephropathy: Hyperbilirubinemia and its Impact on Renal Function
Cholemic nephropathy represents a spectrum of renal injury, from proximal tubulopathy to intrarenal bile cast formation, found in patients with severe liver dysfunction. It is caused by hyperbilirubinemia, usually in jaundiced patients. Acute kidney injury is one of the most important complications...
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| Format: | Article |
| Language: | English |
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Troika Publisher
2019-03-01
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| Series: | Journal of Renal and Hepatic Disorders |
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| Online Access: | https://jrenhep.com/index.php/jrenhep/article/view/52 |
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| author | Jonathan S Chávez-Iñiguez Alejandra Meza-Ríos Arturo Santos-Garcia Guillermo García-García Juan Armendáriz-Borunda |
| author_facet | Jonathan S Chávez-Iñiguez Alejandra Meza-Ríos Arturo Santos-Garcia Guillermo García-García Juan Armendáriz-Borunda |
| author_sort | Jonathan S Chávez-Iñiguez |
| collection | DOAJ |
| description | Cholemic nephropathy represents a spectrum of renal injury, from proximal tubulopathy to intrarenal bile cast formation, found in patients with severe liver dysfunction. It is caused by hyperbilirubinemia, usually in jaundiced patients. Acute kidney injury is one of the most important complications in patients with end-stage liver disease. The relationship between liver disease and renal impairment, especially the effect of hyperbilirubinemia on renal tissue and renal function, has not been fully elucidated. These considerations deem necessary for nephrologists, when performing a clinical evaluation of patients with liver diseases, for the implementation of an integrated medical approach. This review focuses on the current knowledge on cholemic nephropathy with emphasis on the role of hyperbilirubinemia on renal impairment. The treatment strategies and outcome are also discussed. |
| format | Article |
| id | doaj-art-308f85769eff4b44b29c8dde204f1d9b |
| institution | Matheson Library |
| issn | 2207-3744 |
| language | English |
| publishDate | 2019-03-01 |
| publisher | Troika Publisher |
| record_format | Article |
| series | Journal of Renal and Hepatic Disorders |
| spelling | doaj-art-308f85769eff4b44b29c8dde204f1d9b2025-07-02T05:31:03ZengTroika PublisherJournal of Renal and Hepatic Disorders2207-37442019-03-013110.15586/jrenhep.2019.52Cholemic Nephropathy: Hyperbilirubinemia and its Impact on Renal FunctionJonathan S Chávez-Iñiguez0Alejandra Meza-Ríos1Arturo Santos-Garcia2Guillermo García-García3Juan Armendáriz-Borunda4Servicio de Nefrología, Hospital Civil de Guadalajara Fray Antonio Alcalde, Guadalajara, Jalisco, MéxicoTecnologico de Monterrey, Campus Guadalajara, MexicoTecnologico de Monterrey, Campus Guadalajara, MexicoCentro Universitario de Ciencias de la Salud CUCS, Universidad de Guadalajara, Guadalajara, Jalisco, MéxicoInstituto de Biología Molecular en Medicina y Terapia Génica, CUCS, Universidad de Guadalajara, Jalisco, MéxicoCholemic nephropathy represents a spectrum of renal injury, from proximal tubulopathy to intrarenal bile cast formation, found in patients with severe liver dysfunction. It is caused by hyperbilirubinemia, usually in jaundiced patients. Acute kidney injury is one of the most important complications in patients with end-stage liver disease. The relationship between liver disease and renal impairment, especially the effect of hyperbilirubinemia on renal tissue and renal function, has not been fully elucidated. These considerations deem necessary for nephrologists, when performing a clinical evaluation of patients with liver diseases, for the implementation of an integrated medical approach. This review focuses on the current knowledge on cholemic nephropathy with emphasis on the role of hyperbilirubinemia on renal impairment. The treatment strategies and outcome are also discussed.https://jrenhep.com/index.php/jrenhep/article/view/52cholemic nephtropathyextracorporeal albumin dialysishyperbilirubinemiamolecular adsorbent recirculating systemursodeoxycholic acid |
| spellingShingle | Jonathan S Chávez-Iñiguez Alejandra Meza-Ríos Arturo Santos-Garcia Guillermo García-García Juan Armendáriz-Borunda Cholemic Nephropathy: Hyperbilirubinemia and its Impact on Renal Function Journal of Renal and Hepatic Disorders cholemic nephtropathy extracorporeal albumin dialysis hyperbilirubinemia molecular adsorbent recirculating system ursodeoxycholic acid |
| title | Cholemic Nephropathy: Hyperbilirubinemia and its Impact on Renal Function |
| title_full | Cholemic Nephropathy: Hyperbilirubinemia and its Impact on Renal Function |
| title_fullStr | Cholemic Nephropathy: Hyperbilirubinemia and its Impact on Renal Function |
| title_full_unstemmed | Cholemic Nephropathy: Hyperbilirubinemia and its Impact on Renal Function |
| title_short | Cholemic Nephropathy: Hyperbilirubinemia and its Impact on Renal Function |
| title_sort | cholemic nephropathy hyperbilirubinemia and its impact on renal function |
| topic | cholemic nephtropathy extracorporeal albumin dialysis hyperbilirubinemia molecular adsorbent recirculating system ursodeoxycholic acid |
| url | https://jrenhep.com/index.php/jrenhep/article/view/52 |
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