WTAP promotes lipopolysaccharides-induced ferroptosis in human renal tubular epithelial cells by regulating ACSL4 m6A methylation

WTAP promotes lipopolysaccharides-induced ferroptosis in human renal tubular epithelial cells by regulating ACSL4 m6A methylation

Objective To investigate the role of Wilms' tumor 1-associating protein (WTAP) in lipopolysaccharide (LPS) induced ferroptosis in human renal tubular epithelial cells (HK-2) and its molecular mechanism.Methods Expression differences of WTAP and long chain acyl-CoA synthetase 4 (ACSL4) between a...

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Bibliographic Details
Main Authors: ZHANG Qin, TANG Qing, CHEN Bingyang
Format: Article
Language:Chinese
Published: Editorial Office of New Medicine 2025-07-01
Series:Yixue xinzhi zazhi
Subjects:
wilms' tumor 1-associating protein
long chain acyl-coa synthetase 4
n6-methyladenosine
ferroptosis
sepsis
Online Access:https://yxxz.whuznhmedj.com/futureApi/storage/attach/2507/DcKEJgusHFkzayiyIBPWC9KUDYH4xxlafsCewVhn.pdf
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