A Real-Time High-Resolution Multi-Focus Image Fusion Algorithm Based on Multi-Scale Feature Aggregation

In microscopic imaging, the key to obtaining a fully clear image lies in effectively extracting and fusing the sharp regions from different focal planes. However, traditional multi-focus image fusion algorithms have high computational complexity, making it difficult to achieve real-time processing o...

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Bibliographic Details
Main Authors: Huawei Chen, Xingkai Du, Hongchuan Huang, Tingyu Zhao
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Applied Sciences
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Online Access:https://www.mdpi.com/2076-3417/15/13/6967
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Summary:In microscopic imaging, the key to obtaining a fully clear image lies in effectively extracting and fusing the sharp regions from different focal planes. However, traditional multi-focus image fusion algorithms have high computational complexity, making it difficult to achieve real-time processing on embedded devices. We propose an efficient high-resolution real-time multi-focus image fusion algorithm based on multi-aggregation. we use a difference of Gaussians image and a Laplacian pyramid for focused region detection. Additionally, the image is down-sampled before the focused region detection, and up-sampling is applied at the output end of the decision map, thereby reducing 75% of the computational data volume. The experimental results show that the proposed algorithm excels in both focused region extraction and computational efficiency evaluation. It achieves comparable image fusion quality to other algorithms while significantly improving processing efficiency. The average time for multi-focus image fusion with a 4K resolution image on embedded devices is 0.586 s. Compared with traditional algorithms, the proposed method achieves a 94.09% efficiency improvement on embedded devices and a 21.17% efficiency gain on desktop computing platforms.
ISSN:2076-3417