Cell retention in scalable, perfusion-based mesenchymal stem cell expansion processes: a proof of concept
The production of clinically relevant quantities of human mesenchymal stromal cells (hMSCs) requires scalable and intensified manufacturing processes. For this reason, the applicability of alternating tangential flow filtration (ATF) and tangential flow depth filtration (TFDF) based cell retention s...
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Main Authors: | Samuel Lukas Schneider, Abiram Gopalakrishnan, Misha Alexander Teale, Regine Eibl |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2025-07-01
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Series: | Frontiers in Bioengineering and Biotechnology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fbioe.2025.1611703/full |
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