FilaggrinHigh melanomas exhibit active FGFR and allergic signatures with impaired GNA14 and Th1 signatures
Filaggrin gene (FLG/FLG2) product deregulations are associated with various allergic skin diseases, including but not limited to atopic dermatitis, alopecia areata, and ichthyosis vulgaris. However, the molecular immunological underpinnings of filaggrin phenotype manifestations are not completely un...
Saved in:
Main Authors: | Goodwin G. Jinesh, Isha Godwin |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2025-07-01
|
Series: | Frontiers in Genetics |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fgene.2025.1569403/full |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Filaggrin Defect at Atopic Dermatitis: Modern Treatment Options
by: Nikolay N. Murashkin, et al.
Published: (2022-11-01) -
Study of Th1/Th2 cytokine balance status in patients with generalized pruritus
by: YU Hai-yan, et al.
Published: (2004-03-01) -
Filaggrin and Atopic Dermatitis: Clinical and Pathogenetic Parallels and Therapeutic Possibilities
by: Nikolay N. Murashkin, et al.
Published: (2021-11-01) -
Single nucleotide variants of filaggrin and glucocorticoid receptors genes in children suffering different phenotypes of atopic diseases
by: V.O. Dityatkovsky, et al.
Published: (2022-03-01) -
The role of filaggrin mutations leading to a decrease in the amount of protein in the development of atopic dermatitis and bronchial asthma in children
by: S. I. Makarova, et al.
Published: (2021-06-01)