Hepatitis B virus infection in pregnant women in Baghdad

Background: Globally, hepatitis B is one of the  most common infectious diseases. Estimates  indicate that at least 2 billion people have been  infected with the hepatitis B virus (HBV), with  more than 378 million people being chronic  carriers. Those individuals at higher risk for  acquiring HBV...

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Bibliographic Details
Main Author: Hujaz Ismail
Format: Article
Language:English
Published: University of Baghdad/ Al-Kindy College of Medicine 2013-01-01
Series:مجله كليه طب الكندي
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Online Access:https://www.jkmc.uobaghdad.edu.iq/index.php/MEDICAL/article/view/2401
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Summary:Background: Globally, hepatitis B is one of the  most common infectious diseases. Estimates  indicate that at least 2 billion people have been  infected with the hepatitis B virus (HBV), with  more than 378 million people being chronic  carriers. Those individuals at higher risk for  acquiring HBV and transmitting disease like  pregnant women should be screened for  hepatitis  B surface   antigen (HBsAg) to prevent  transmission by vaccination and operation.   Aim of study: The aim of this study was to  determine the prevalence of HBsAg and its  associated parameters in pregnant women who  referred to antenatal clinic in Baghdad Province.  Methods: The 234 apparently healthy pregnant  women and their families, husbands and children  were selected as study subjects from among those  who had attained prenatal care clinic in Baghdad  province between 2010  to 2012. Serological test  was done for HBV using ELISA test (Dialab  REF:Z00360,LOT2052-2).  Results: Of these, 234 cases were brought into the  study. Their age were ranged from 16-42 years old.  Based on a different parameters , women positive  for HBV and their children were negative  constitute the highest percentage 85.4% and lowest  one was pregnant women who lived with positive  family history of HBV were 8.9%.   Conclusions: The seroprevalence of HBsAg was  of moderate severity according to WHO. This  finding would suggest for the introduction of  routine screening for HBV to all pregnant women  during the antenatal period, and that “at birth dose”  vaccination is given to new born babies of mothers  found to be HBsAg positive so as to reduce and  prevent the spread of infection. However more data  is required from larger studies to support the  findings so that ultimately this can be  recommended as a policy. Background: Globally, hepatitis B is one of the  most common infectious diseases. Estimates  indicate that at least 2 billion people have been  infected with the hepatitis B virus (HBV), with  more than 378 million people being chronic  carriers. Those individuals at higher risk for  acquiring HBV and transmitting disease like  pregnant women should be screened for  hepatitis  B surface   antigen (HBsAg) to prevent  transmission by vaccination and operation.   Aim of study: The aim of this study was to  determine the prevalence of HBsAg and its  associated parameters in pregnant women who  referred to antenatal clinic in Baghdad Province.  Methods: The 234 apparently healthy pregnant  women and their families, husbands and children  were selected as study subjects from among those  who had attained prenatal care clinic in Baghdad  province between 2010  to 2012. Serological test  was done for HBV using ELISA test (Dialab  REF:Z00360,LOT2052-2).  Results: Of these, 234 cases were brought into the  study. Their age were ranged from 16-42 years old.  Based on a different parameters , women positive  for HBV and their children were negative  constitute the highest percentage 85.4% and lowest  one was pregnant women who lived with positive  family history of HBV were 8.9%.   Conclusions: The seroprevalence of HBsAg was  of moderate severity according to WHO. This  finding would suggest for the introduction of  routine screening for HBV to all pregnant women  during the antenatal period, and that “at birth dose”  vaccination is given to new born babies of mothers  found to be HBsAg positive so as to reduce and  prevent the spread of infection. However more data  is required from larger studies to support the  findings so that ultimately this can be  recommended as a policy. Background: Globally, hepatitis B is one of the  most common infectious diseases. Estimates  indicate that at least 2 billion people have been  infected with the hepatitis B virus (HBV), with  more than 378 million people being chronic  carriers. Those individuals at higher risk for  acquiring HBV and transmitting disease like  pregnant women should be screened for  hepatitis  B surface   antigen (HBsAg) to prevent  transmission by vaccination and operation.   Aim of study: The aim of this study was to  determine the prevalence of HBsAg and its  associated parameters in pregnant women who  referred to antenatal clinic in Baghdad Province.  Methods: The 234 apparently healthy pregnant  women and their families, husbands and children  were selected as study subjects from among those  who had attained prenatal care clinic in Baghdad  province between 2010  to 2012. Serological test  was done for HBV using ELISA test (Dialab  REF:Z00360,LOT2052-2).  Results: Of these, 234 cases were brought into the  study. Their age were ranged from 16-42 years old.  Based on a different parameters , women positive  for HBV and their children were negative  constitute the highest percentage 85.4% and lowest  one was pregnant women who lived with positive  family history of HBV were 8.9%.   Conclusions: The seroprevalence of HBsAg was  of moderate severity according to WHO. This  finding would suggest for the introduction of  routine screening for HBV to all pregnant women  during the antenatal period, and that “at birth dose”  vaccination is given to new born babies of mothers  found to be HBsAg positive so as to reduce and  prevent the spread of infection. However more data  is required from larger studies to support the  findings so that ultimately this can be  recommended as a policy. Background: Globally, hepatitis B is one of the  most common infectious diseases. Estimates  indicate that at least 2 billion people have been  infected with the hepatitis B virus (HBV), with  more than 378 million people being chronic  carriers. Those individuals at higher risk for  acquiring HBV and transmitting disease like  pregnant women should be screened for  hepatitis  B surface   antigen (HBsAg) to prevent  transmission by vaccination and operation.   Aim of study: The aim of this study was to  determine the prevalence of HBsAg and its  associated parameters in pregnant women who  referred to antenatal clinic in Baghdad Province.  Methods: The 234 apparently healthy pregnant  women and their families, husbands and children  were selected as study subjects from among those  who had attained prenatal care clinic in Baghdad  province between 2010  to 2012. Serological test  was done for HBV using ELISA test (Dialab  REF:Z00360,LOT2052-2).  Results: Of these, 234 cases were brought into the  study. Their age were ranged from 16-42 years old.  Based on a different parameters , women positive  for HBV and their children were negative  constitute the highest percentage 85.4% and lowest  one was pregnant women who lived with positive  family history of HBV were 8.9%.   Conclusions: The seroprevalence of HBsAg was  of moderate severity according to WHO. This  finding would suggest for the introduction of  routine screening for HBV to all pregnant women  during the antenatal period, and that “at birth dose”  vaccination is given to new born babies of mothers  found to be HBsAg positive so as to reduce and  prevent the spread of infection. However more data  is required from larger studies to support the  findings so that ultimately this can be  recommended as a policy. 
ISSN:1810-9543
2521-4365