Progress in potential toxicity of chiral pesticides

In the past, chiral pesticides were explored as racemic mixtures in environmental fate and ecotoxicities. However, as a result of the enantioselective interactions with chiral molecules, the enantiomers of chiral pesticides may have different potential toxicities to humans and animals. The present r...

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Main Authors: LIU Wei-ping, ZHANG Ying
Format: Article
Language:English
Published: Zhejiang University Press 2012-01-01
Series:浙江大学学报. 农业与生命科学版
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Online Access:https://www.academax.com/doi/10.3785/j.issn.1008-9209.2012.01.009
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author LIU Wei-ping
ZHANG Ying
author_facet LIU Wei-ping
ZHANG Ying
author_sort LIU Wei-ping
collection DOAJ
description In the past, chiral pesticides were explored as racemic mixtures in environmental fate and ecotoxicities. However, as a result of the enantioselective interactions with chiral molecules, the enantiomers of chiral pesticides may have different potential toxicities to humans and animals. The present review introduced recent findings on enantioselective endocrine disruption, neurotoxicity, immunotoxicity, reproductive and developmental toxicity of organophosphorus, organochlorines, pyrethroids and phenylpyrazole pesticides, as well as the underlying mechanisms. Furthermore, the developmental trends of future investigations were discussed.
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series 浙江大学学报. 农业与生命科学版
spelling doaj-art-2daf8b05a04d454b9da14ffa65b181082025-08-01T05:33:26ZengZhejiang University Press浙江大学学报. 农业与生命科学版1008-92092097-51552012-01-0138637010.3785/j.issn.1008-9209.2012.01.00910089209Progress in potential toxicity of chiral pesticidesLIU Wei-pingZHANG YingIn the past, chiral pesticides were explored as racemic mixtures in environmental fate and ecotoxicities. However, as a result of the enantioselective interactions with chiral molecules, the enantiomers of chiral pesticides may have different potential toxicities to humans and animals. The present review introduced recent findings on enantioselective endocrine disruption, neurotoxicity, immunotoxicity, reproductive and developmental toxicity of organophosphorus, organochlorines, pyrethroids and phenylpyrazole pesticides, as well as the underlying mechanisms. Furthermore, the developmental trends of future investigations were discussed.https://www.academax.com/doi/10.3785/j.issn.1008-9209.2012.01.009chiral pesticidesenantioselectivityendocrine disruptionneurotoxicityimmunotoxicitydevelopmental toxicitytoxic mechanism
spellingShingle LIU Wei-ping
ZHANG Ying
Progress in potential toxicity of chiral pesticides
浙江大学学报. 农业与生命科学版
chiral pesticides
enantioselectivity
endocrine disruption
neurotoxicity
immunotoxicity
developmental toxicity
toxic mechanism
title Progress in potential toxicity of chiral pesticides
title_full Progress in potential toxicity of chiral pesticides
title_fullStr Progress in potential toxicity of chiral pesticides
title_full_unstemmed Progress in potential toxicity of chiral pesticides
title_short Progress in potential toxicity of chiral pesticides
title_sort progress in potential toxicity of chiral pesticides
topic chiral pesticides
enantioselectivity
endocrine disruption
neurotoxicity
immunotoxicity
developmental toxicity
toxic mechanism
url https://www.academax.com/doi/10.3785/j.issn.1008-9209.2012.01.009
work_keys_str_mv AT liuweiping progressinpotentialtoxicityofchiralpesticides
AT zhangying progressinpotentialtoxicityofchiralpesticides