Clinical significance of determining neutrophil extracellular traps in women with oncogynecological neoplasms

The formation of neutrophil extracellular traps (NETs), described first in 2004 as a previously unknown neutrophil strategy for combating microbes, has been attracting a growing interest in research community. NETs play a key role in inflammation and infection exploiting effector functions such as d...

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Main Authors: Z. D. Aslanova, J. Kh. Khizroeva, A. G. Solopova, V. A. Solodkiy, A. V. Vorobev, D. V. Blinov, M. D. Aslanova, I. A. Nakaidze, J.-C. Gris, I. Elalamy, A. D. Makatsariya
Format: Article
Language:Russian
Published: IRBIS LLC 2024-01-01
Series:Акушерство, гинекология и репродукция
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Online Access:https://www.gynecology.su/jour/article/view/1856
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Summary:The formation of neutrophil extracellular traps (NETs), described first in 2004 as a previously unknown neutrophil strategy for combating microbes, has been attracting a growing interest in research community. NETs play a key role in inflammation and infection exploiting effector functions such as degranulation, phagocytosis as well as production of reactive oxygen species (ROS). NETs play a crucial role in defense against systemic infections. Additionally NETs involved in inflammation, and in the pathogenesis of non-infectious diseases, such as autoimmune diseases and cancer.
ISSN:2313-7347
2500-3194