Inhibitor development and clinical characteristics in children with severe hemophilia A in the ATHN 8 US cohort study

Inhibitor development and clinical characteristics in children with severe hemophilia A in the ATHN 8 US cohort study

Abstract: Clotting factor concentrate (CFC), used to treat and prevent bleeding in hemophilia, is rendered ineffective if clotting factor neutralizing antibodies (inhibitors) develop. Inhibitors occur most often in children, early in treatment. The American Thrombosis and Hemostasis Network (ATHN) 8...

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Main Authors: Courtney D. Thornburg, H. Marijke van den Berg, Martin Chandler, Lynn Malec, Matthew Manuel, Carrie O’Neill, Michael Recht, Elizabeth Taggart, Shannon L. Carpenter, Christine Knoll, Michael Wang, Michael Guerrera, Cristina Tarango, Robert Sidonio, Nidra Rodriguez, Kenneth D. Friedman, Amy Shapiro, Hassan Yaish, Shannon Carpenter, Maissaa Janbain, Eric Grabowski, Rajiv Pruthi, Kristina Haley, Courtney Thornburg, Sanjay Ahuja, Mindy Simpson, Ulrike Reiss, Tiffany Lucas, Vinod Balasa, Allison Wheeler
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Blood Vessels, Thrombosis & Hemostasis
Online Access:http://www.sciencedirect.com/science/article/pii/S2950327225000397
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