LABORATORY AND GENETIC PREDICTION OF THE RISK OF ATRIAL FIBRILLATION IN PATIENTS WITH CORONARY HEART DISEASE
The paper studied the frequency of polymorphisms of hemostasis in patients with coronary heart disease, living in the Krasnodar region. Of the 13 patients with atrial fibrillation documented confirmed, 11 patients revealed mutations of genes of the hemostatic system (84.61 %), while 10 patients out...
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| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
| Published: |
Ministry of Healthcare of the Russian Federation. “Kuban State Medical University”
2017-05-01
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| Series: | Кубанский научный медицинский вестник |
| Subjects: | |
| Online Access: | https://ksma.elpub.ru/jour/article/view/676 |
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| Summary: | The paper studied the frequency of polymorphisms of hemostasis in patients with coronary heart disease, living in the Krasnodar region. Of the 13 patients with atrial fibrillation documented confirmed, 11 patients revealed mutations of genes of the hemostatic system (84.61 %), while 10 patients out of 11 had a mutation MTRR mutation (90.9 %), and met mutations in polygenic 10 cases (90.9 %). It is shown that the most common mutation MTRR gene, PAI, VII factor and beta fibrin often cause arrhythmias in patients enhance remodeling of the left ventricle, especially in polygenic mutations. |
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| ISSN: | 1608-6228 2541-9544 |