Ectopic Expansion of Pulmonary Vasculature in Fibrotic Lung Disease and Lung Adenocarcinoma Marked by Proangiogenic COL15A1+ Endothelial Cells

Ectopic Expansion of Pulmonary Vasculature in Fibrotic Lung Disease and Lung Adenocarcinoma Marked by Proangiogenic COL15A1+ Endothelial Cells

ABSTRACT Lung vasculature arises from both pulmonary and systemic (bronchial) circulations. Remodeling and structural changes in lung vasculature have been recognized in end‐stage fibrotic lung diseases such as idiopathic pulmonary fibrosis (IPF) but have not been well characterized. The vasculature...

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Bibliographic Details
Main Authors: Eric Engelbrecht, Tristan Kooistra, Nathalie Burg, Lida Hariri, Trong Nguyen, Patricia Brazee, Timothy Hla, Bernadette R. Gochuico, Rachel S. Knipe
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Pulmonary Circulation
Subjects:
collagen 15A1
endothelium
pulmonary fibrosis
Online Access:https://doi.org/10.1002/pul2.70102
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